iNOS (phospho Tyr151) Antibody Cat. No.: 79-877

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse
IMMUNOGEN: iNOS (phospho Tyr151) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 151 (Q-Y-Y (p)-G-S) derived from Human iNOS .
TESTED APPLICATIONS: IHC
SPECIFICITY: The antibody detects endogenous levels of Inos only when phosphorylated at tyrosine 151.
PREDICTED MOLECULAR WEIGHT: 131 kDa

psi-iconProperties
PURIFICATION:Antibodies were purified by affinity-chromatography using epitope-specific peptide.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:Store antibody at -20˚C for up to one year.

psi-iconAdditional Info
OFFICIAL SYMBOL:NOS2
ALTERNATE NAMES:HEP-NOS, NOS2, inducible
ACCESSION NO.:NP_000616.3
PROTEIN GI NO.:1352513
GENE ID:4843
psi-iconBackground and References
BACKGROUND:Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
REFERENCES:1) Geller D.A., Proc. Natl. Acad. Sci. U.S.A. 90:3491-3495(1993).
2) Sherman P.A., Biochemistry 32:11600-11605(1993).
3) Charles I.G., Proc. Natl. Acad. Sci. U.S.A. 90:11419-11423(1993).

ANTIBODIES FOR RESEARCH USE ONLY.

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