SARS-CoV-2 Antibodies Validated with Patient Samples

SARS-CoV-2 (COVID-19, 2019-nCoV) research reagents - antibodies and proteins from ProSci Inc. - the SARS-CoV-2 structure. 

ProSci offers a comprehensive catalog of SARS-CoV-2 antibodies and recombinant proteins for COVID-19 research representing the entire SARS-CoV-2 proteome. Featured on this page are SARS-CoV-2 antibodies validated in ELISA and WB, and importantly, validated with patient samples in IHC and IF. Epitope recognition differs within the Spike antibodies, providing latitude in co-localization studies: Cat. No. 3525 recognizes the C-terminal domain of S2, which to date is a conserved sequence in all SARS-CoV viruses; Cat. No. 9083 recognizes the N-terminal domain of SARS-CoV-2 Spike S1; Cat. No. 9087 recognizes Spike RBD. The sequences of Nucleocapsid, Envelope and Membrane proteins are to date conserved such that ProSci antibodies for each of these structural proteins provide valuable reagents for viral infectious disease and vaccine research including investigative histopathology. Click to learn more about the interaction of ProSci antibodies with variant SARS-CoV-2 proteins.

In addition, Sun et al. (2021) have developed an IHC protocol focused on the use of 9083 and 9099. "Sensitive and Specific Immunohistochemistry Protocol for Nucleocapsid Protein from All Common SARS-CoV-2 Virus Strains in Formalin-Fixed, Paraffin-Embedded Tissues" Methods Protoc. 2021 10;4(3) 47 PMID: 34287344 (unpublished images). ProSci offers additional antibody methods and protocols used in all our validation studies.

Nucleocapsid Antibody Cat No. 9099 and Spike S1 Antibody Cat No. 9083 | ProSci Inc


Validated Antibodies against Structural Proteins

ProductCat. No.ApplicationClonalitySpecies
SARS-CoV-2 (COVID-19) Spike S1 Antibody 9083 E, WB, IHC, IF Polyclonal Rabbit
SARS-CoV-2 (COVID-19) Spike S2 Antibody 3525 E, WB, IHC, IF Polyclonal Rabbit
SARS-CoV-2 (COVID-19) Spike S2 Antibody 9123 E, WB, IHC, IF Polyclonal Rabbit
SARS-CoV-2 (COVID-19) Spike RBD Antibody 9087 E, WB, IHC, IF Polyclonal Rabbit
SARS-CoV-2 (COVID-19) Envelope Antibody 9169 E, WB, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Antibody 3531 E, IHC, IF Polyclonal Rabbit
SARS-CoV-2 (COVID-19) Membrane Antibody 9157 E, WB, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19) Membrane Antibody 9165 E, WB, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19) Nucleocapsid Antibody 9099 E, WB, IHC Polyclonal Rabbit


Validated Antibodies against Non-structural Proteins

ProductCat. No.ApplicationClonalitySpecies
SARS-CoV-2 (COVID-19) NSP2 Antibody 9173 E, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) Antibody 9153 E, WB, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19) NSP7 Antibody 9155 E, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19) NSP8 Antibody 9159 E, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19) NSP9 Antibody 9161 E, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19) NSP10 Antibody 9179 E, WB, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19) NSP13 (Helicase) Antibody 9181 E, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19) NSP13 (Helicase) Antibody 9183 E, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19) NSP14 (ExoN) Antibody 9185 E, IHC Polyclonal Rabbit
SARS-CoV-2 (COVID-19) NSP16 Antibody 9271 E, WB, IHC Polyclonal Rabbit