INF2 Antibody Cat. No.: 8631

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human
HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse: (100%), Frog (71%)
IMMUNOGEN: INF2 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human INF2.
TESTED APPLICATIONS: ELISA, WB
APPLICATIONS: INF2 antibody can be used for Western blot at 1 - 2 μg/mL.

Antibody validated: Western Blot in human and rat samples. All other applications and species not yet tested.
SPECIFICITY: INF2 Antibody is predicted to not cross-react with other INF1.
POSITIVE CONTROL:1) Cat. No. 1202 - A431 Cell Lysate
PREDICTED MOLECULAR WEIGHT: Predicted: 137 kDa

Observed: 160 kDa

psi-iconProperties
PURIFICATION:INF2 Antibody is affinity chromatography purified via peptide column.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:INF2 Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:INF2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:INF2
ALTERNATE NAMES:INF2 Antibody: FSGS5, CMTDIE, C14orf151, C14orf173
ACCESSION NO.:NP_071934
GENE ID:64423
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:INF2 is a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5

ANTIBODIES FOR RESEARCH USE ONLY.

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