Datasheet

INF2 Antibody
CATALOG NUMBER: 8631

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Specifications
Properties
Additional Info
Background

Specifications

SPECIES REACTIVITY:Human
HOMOLOGY:Predicted species reactivity based on immunogen sequence: Mouse: (100%), Frog (71%)
TESTED APPLICATIONS:ELISA, WB
APPLICATIONS:INF2 antibody can be used for Western blot at 1 - 2 μg/mL.
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
POSITIVE CONTROL:1) Cat. No. 1202 - A431 Cell Lysate
PREDICTED MOLECULAR WEIGHT:Predicted: 137 kDa

Observed: 160 kDa
SPECIFICITY:INF2 Antibody is predicted to not cross-react with other INF1.
IMMUNOGEN:INF2 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human INF2.
HOST SPECIES:Rabbit

Properties

PURIFICATION:INF2 Antibody is affinity chromatography purified via peptide column.
PHYSICAL STATE:Liquid
BUFFER:INF2 Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:INF2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated

Additional Info

ALTERNATE NAMES:INF2 Antibody: FSGS5, CMTDIE, C14orf151, C14orf173
ACCESSION NO.:NP_071934
OFFICIAL SYMBOL:INF2
GENE ID:64423

Background

BACKGROUND:INF2 is a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5

For Research Use Only