PD-L1 Immune Checkpoint

 

PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. PD-L1 can bind to PD-1, which mediates inhibitory signals from the APC.


Match Pair Sets

A sandwich ELISA was performed using the anti-PD-L1 mAbs RF16031, RF16032, RF16033, and RF16034 as the capture antibodies for the PD-1 extracellular domain antigen with anti-PD-1 sdAbs SD8585, SD8623, SD8639, and SD8641 as the detection antibodies.

TargetCat. No.CaptureDetectionHostDatasheet
PD-L1 Human Matched Antibody Pair #1
*See Capture ELISA Data*PD-L1 Matched Pair ELISA Data
RFP-0303 RF16031 SD8639 Mouse - Llama
PD-L1 Human Matched Antibody Pair #2
*See Capture ELISA Data*PD-L1 Matched Pair ELISA Data
RFP-0306 RF16032 SD8639 Mouse - Llama

Risk-Free™ Mouse Monoclonal PD-L1 Products

ProSci's Risk-Free™ antibodies are monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-Free™ antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Risk-Free™ means they are guaranteed to work for their approved applications.
"Hover over research application to see respective image (if available)."

Risk-Free™ Mouse Monoclonal PD-L1 Set

ProSci's Risk-Free™ Sets consists of several mAbs with different binding features allowing selection of the best clone.

Product SetSizeContentsDescription
Risk-Free PD-L1 Set (RF16030) 20μg / Clone RF16031, RF16032, RF16033 RF16035, RF16036, RF16037, RF16038 PD-L1 antibodies were raised against the extracellular domain of human PD-L1.

Risk-Free™ Mouse Monoclonal PD-L1 Antibodies

ProSci Risk-Free™ PD-L1 products are rigorously tested and guaranteed to work for their designated applications.

= Negative = Fair   = Average    = Good     = Excellent= Best Application
Cat. No.ELISAWBICCIFIHCFlowConjugation
RF16031 Host Species: Mouse
Reactivity: Human
 
ELISA Titration Curve Analysis
   
WB in HEK293 Cells
   
ICC in HEK293 Cells
  
IF in HEK293 Cells
   
IHC in Human Tonsil
   
Flow in HEK293 Cells
Available
RF16032Host Species: Mouse
Reactivity: Human
 
ELISA Titration Curve Analysis
   
WB in HEK293 Cells
   
ICC in HEK293 Cells
 
IF in HEK293 Cells
   
IHC in Human Tonsil
   
Flow in HEK293 Cells
Available
RF16033Host Species: Mouse
Reactivity: Human
         
ICC in HEK293 Cells
  
IF in HEK293 Cells
   
IHC in Human Tonsil
   
Flow in HEK293 Cells
Available
RF16035Host Species: Mouse
Reactivity: Human
   
ELISA Titration Curve Analysis
 
WB in HEK293 Cells
   
ICC in HEK293 Cells
  
IF in HEK293 Cells
  
IHC in Human Tonsil
   Available
RF16036Host Species: Mouse
Reactivity: Human
   
ELISA Titration Curve Analysis
  
WB in HEK293 Cells
   
ICC in HEK293 Cells
   
IF in HEK293 Cells
  
IHC in Human Tonsil
   Available
RF16037Host Species: Mouse
Reactivity: Human
   
ELISA Titration Curve Analysis
  
WB in HEK293 Cells
   
ICC in HEK293 Cells
  
IF in HEK293 Cells
   
IHC in Human Tonsil
   Available
RF16038Host Species: Mouse
Reactivity: Human
   
ELISA Titration Curve Analysis
  
WB in HEK293 Cells
   
ICC in HEK293 Cells
   
IF in HEK293 Cells
   
IHC in Human Tonsil
   Available

Risk-Free™ Single Domain Monoclonal PD-L1 Products

Llama single domain antibodies (sdAbs) offer unique characteristics amenable to many applications. These sdAbs demonstrate low nanomolar binding affinity and can be used for the various applications. Note: PD-L1 antibody should be stored in working aliquots at -20 °C, stable for up to one year. As with all antibodies, care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Risk-Free™ Single Domain Monoclonal PD-L1 Antibodies

= Not Yet Determined = Negative = Fair   = Average    = Good     = Excellent
Cat. No.CloneELISAWBICCIFIHCFlowFunctionalityDatasheet
SD8639Host Species: Llama
Reactivity: Human
F6A9                 
Flow in HEK293 Cells
  
SD8641Host Species: Llama
Reactivity: Human
F2G2    
Titration ELISA
                 

Related Products

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Antigen


Cat. No.Product TypeSpeciesTissue/CellDatasheet
RF16030-01 Recombinant Protein Human HEK293
 
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Lysates


Cat. No.Product TypeSpeciesTissue/CellDatasheet
RF10001-06 Positive Control (Cell Lysate) Human Raji
RF10001-04 Positive Control (Tissue Lysate) Human Tonsil
RF10001-02 Negative Control (Cell Lysate) Human HEK293
 
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Slides


Cat. No.Product TypeSpeciesTissue/CellDatasheet
RF10002-04 Positive Control (Cells) Human Raji
RF10002-02 Negative Control (Cells) Human HEK293
 
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Conjugates


Cat. No.HRPBiotinCustom
RF16031 Inquire Contact Us
RF16032 Inquire Contact Us
RF16033 Inquire Contact Us
RF16035 Inquire Contact Us
RF16036 Inquire Contact Us
RF16037 Inquire Contact Us
RF16038 Inquire Contact Us
 

Additional Antibody PD-L1 Products

Monoclonal antibodies are highly specific and recognize only one epitope on an antigen which generates consistent performance in quantitative detection applications regardless of production batch. Polyclonal antibodies have high affinity and recognize different epitopes on a specific antigen. Note: These antibodies can be stored at -20˚C and are stable for up to one year. Antibodies should not be exposed to prolonged high temperatures.


Monoclonal PD-L1 Products

Cat. No.NameApplicationsDatasheet
76-958Host Species: Rat
Reactivity: Mouse
CD274 Antibody [10F.9G2] Flow, Func
76-960Host Species: Rat
Reactivity: Mouse
CD274 Antibody [10F.9G2] (PE) Flow

Polyclonal PD-L1 Products

= Not Yet Determined = Negative = Fair   = Average    = Good     = Excellent
Cat. No.Antigen RangeELISAWBICCIFIHCFlowDatasheet
4059Host Species: Rabbit
Reactivity: HU, MS, RAT
60 - 110       
WB in Raji
      
IF in Human Heart
  
IHC in Human Tonsil
  
Flow Analysis
46-156Host Species: Goat
Reactivity: Human
240 - 290      
WB in Human Heart
         
IHC in Human Placenta
  

PD-L1 Recombinant Protein Products

Cat. No.SequenceFusion TagSpeciesTissue/CellDatasheet
90-429 Aa 19 - 238 Fc Tag Human CHO
90-430 Aa 19 - 238 Fc Tag Human [Non-Lytic] CHO
90-431 Aa 19 - 237 Fc Tag Mouse CHO
90-432 Aa 19 - 237 Fc Tag Mouse [Non-Lytic] CHO
91-293 Phe 19 - Thr 239 C-6 His tag Human Human
92-625 Phe 19 - Thr 239 C-Flag Tag Human Human
96-598 Phe 19 - Arg 238 C-Fc Tag Human HEK293
96-599 Phe 19 - Arg 238 C-Twin Strep Tag Human HEK293
96-606 Phe 19 - Arg 238 His Tag Human HEK293
96-608 Phe 19 - Thr 238 His Tag Human HEK293
96-610 Phe 19 - Thr 238 C-Fc Tag Mouse HEK293

PD-L1 Peptide Products

Cat. No.LocationSpeciesDatasheet
4059P 17 amino acids near the center of human PD-L1 Human
46-156P PD-L1 peptide corresponds to 12 amino acids of PD-L1 Human

Additional PD-L1 Information

 

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