LIGHT Immune Checkpoint
LIGHT (CD258) is a type II membrane protein belonging to the TNF family of membrane-anchored ligands. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells.
Risk-Free™ Monoclonal LIGHT Products
ProSci's Risk-Free™ antibodies are monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-Free™ antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Risk-Free™ means they are guaranteed to work for their approved applications.
"Hover over research application to see respective image (if available)."
Risk-Free™ Mouse Monoclonal LIGHT Set
ProSci's Risk-Free™ Sets consists of several mAbs with different binding features allowing selection of the best clone.
| Product Set | Size | Contents | Description |
|---|---|---|---|
| Risk-Free LIGHT Set (RF16060) | 20μg / Clone | RF16061, RF16062, RF16063, RF16064 | LIGHT antibodies were raised against the extracellular domain of human LIGHT. |
Risk-Free™ Mouse Monoclonal LIGHT Antibodies
ProSci Risk-Free™ LIGHT products are rigorously tested and guaranteed to work for their designated applications.
| Cat. No. | ELISA | WB | ICC | IF | IHC | Flow | Conjugation |
|---|---|---|---|---|---|---|---|
| RF16061 Host Species: Mouse Reactivity: Human |
 ELISA Titration Curve Analysis |
 WB in HEK293 Cells |
 ICC in HEK293 Cells |
 IF in HEK293 Cells |
 IHC in Human Lymphoma |
 Flow in HEK293 Cells |
Available |
| RF16062 Host Species: Mouse Reactivity: Human |
ELISA Titration Curve Analysis |
WB in HEK293 Cells |
 ICC in HEK293 Cells |
 IF in HEK293 Cells |
 IHC in Human Lymphoma |
 Flow in HEK293 Cells |
Available |
| RF16063 Host Species: Mouse Reactivity: Human |
ELISA Titration Curve Analysis |
WB in HEK293 Cells |
 ICC in HEK293 Cells |
 IF in HEK293 Cells |
 IHC in Human Lymphoma |
 Flow in HEK293 Cells |
Available |
| RF16064 Host Species: Mouse Reactivity: Human |
ELISA Titration Curve Analysis |
WB in HEK293 Cells |
 ICC in HEK293 Cells |
 IF in HEK293 Cells |
 IHC in Human Lymphoma |
 Flow in HEK293 Cells |
Available |
= Best Application
Risk-Free™ Single Domain Monoclonal LIGHT Products
Llama single domain antibodies (sdAbs) offer unique characteristics amenable to many applications. These sdAbs demonstrate low nanomolar binding affinity and can be used for the various applications. Note: LIGHT single domain antibody should be stored in working aliquots at -20 °C, stable for up to one year. As with all antibodies, care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
If you are interested in the development
of a LIGHT single domain antibody, let us know.
Related Products
Antigens
| Cat. No. | Product Type | Species | Tissue/Cell | Datasheet |
|---|---|---|---|---|
| RF16060-01 | Recombinant Protein | Human | HEK293 |
PDF Lysates
| Cat. No. | Product Type | Species | Tissue/Cell | Datasheet |
|---|---|---|---|---|
| RF10001-02 | Negative Control (Cell Lysate) | Human | HEK293 |
Slides
| Cat. No. | Product Type | Species | Tissue/Cell | Datasheet |
|---|---|---|---|---|
| RF10001-02 | Negative Control (Cell Lysate) | Human | HEK293 |
Conjugates
| Cat. No. | HRP | Biotin | Custom |
|---|---|---|---|
| RF16061 | Inquire | Contact Us | |
| RF16062 | Inquire | Contact Us | |
| RF16063 | Inquire | Contact Us | |
| RF16064 | Inquire | Contact Us | |
Additional LIGHT Antibody Products
Monoclonal antibodies are highly specific and recognize only one epitope on an antigen which generates consistent performance in quantitative detection applications regardless of production batch. Polyclonal antibodies have high affinity and recognize different epitopes on a specific antigen. Note: These antibodies can be stored at -20˚C and are stable for up to one year. Antibodies should not be exposed to prolonged high temperatures.
LIGHT Monoclonal Products
No additonal monoclonal antibodies available.
Check out our Risk-Free™ Mouse mAbs.
LIGHT Polyclonal Products
| Cat. No. | Antigen Range | ELISA | WB | ICC | IF | IHC | Flow | Datasheet |
|---|---|---|---|---|---|---|---|---|
| 42-126Host Species: Goat Reactivity: Human |
??? |  WB in EL4 Cell |
||||||
| 57-843Host Species: Rabbit Reactivity: Human |
66 - 94 | WB in EL4 Cell |
||||||
| XP-5215Host Species: Rabbit Reactivity: Human |
??? | WB in EL4 Cell |
||||||
| XP-5215BtHost Species: Rabbit Reactivity: Human |
??? | WB in EL4 Cell |
LIGHT Recombinant Protein Products
| Cat. No. | Sequence | Fusion Tag | Species | Tissue/Cell | Datasheet |
|---|---|---|---|---|---|
| 40-301 | ??? | See product page | Human | High-5 Insect | |
| 40-452 | ??? | See product page | Murine | E. coli | |
| 90-224 | Aa 89 - Aa 240 | DDDDK-Tag | Human, Mouse | CHO |
LIGHT Peptide Products
| Cat. No. | Location | Species | Datasheet |
|---|---|---|---|
| 42-126P | A synthetic peptide cooresponding to 14 amino acids from an internal region of TNFSF14. | Human |
