CD80 Immune Checkpoint

 

CD80, also known as B7-1, is a type I membrane protein that is a member of the immunoglobulin superfamily that is expressed by antigen-presenting cells. Like the related protein CD86, this protein is expressed by antigen-presenting cells and is the ligand for CD28 and CTLA-4 at the cell surface of T cells. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell and induces T-cell proliferation and cytokine production.


Risk-Free™ Mouse Monoclonal CD80 Products

ProSci's Risk-Free™ antibodies are monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-Free™ antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Risk-Free™ means they are guaranteed to work for their approved applications.
"Hover over research application to see respective image (if available)."

Risk-Free™ Mouse Monoclonal CD80 Set

ProSci's Risk-Free™ Sets consists of several mAbs with different binding features allowing selection of the best clone.

Product SetSizeContentsDescription
Risk-Free CD80 Set (RF16040) 20μg / Clone RF16041, RF16042, RF16043, RF16044, RF16045, RF16046 CD80 antibodies were raised against the extracellular domain of human CD-80.

Risk-Free™ Mouse Monoclonal CD80 Antibodies

ProSci Risk-Free™ CD80 products are rigorously tested and guaranteed to work for their designated applications.

= Negative = Fair   = Average    = Good     = Excellent= Best Application
Cat. No.ELISAWBICCIFIHCFlowConjugation
RF16041 Host Species: Mouse
Reactivity: Human
 
ELISA Titration Curve Analysis
      
ICC in HEK293 Cells
   
IF in HEK293 Cells
   
IHC in Human Tonsil
   
Flow in HEK293 Cells
Available
RF16042 Host Species: Mouse
Reactivity: Human
 
ELISA Titration Curve Analysis
      
ICC in HEK293 Cells
   
IF in HEK293 Cells
   
IHC in Human Tonsil
   
Flow in HEK293 Cells
Available
RF16043 Host Species: Mouse
Reactivity: Human
  
ELISA Titration Curve Analysis
      
ICC in HEK293 Cells
   
IF in HEK293 Cells
  
IHC in Human Tonsil
   Available
RF16044 Host Species: Mouse
Reactivity: Human
  
ELISA Titration Curve Analysis
      
ICC in HEK293 Cells
   
IF in HEK293 Cells
  
IHC in Human Tonsil
   
Flow in HEK293 Cells
Available
RF16045 Host Species: Mouse
Reactivity: Human
   
ELISA Titration Curve Analysis
   
WB in HEK293 Cells
   
ICC in HEK293 Cells
   
IF in HEK293 Cells
   
IHC in Human Tonsil
   Available
RF16046 Host Species: Mouse
Reactivity: Human
   
ELISA Titration Curve Analysis
   
WB in HEK293 Cells
   
ICC in HEK293 Cells
   
IF in HEK293 Cells
   
IHC in Human Tonsil
   Available

Risk-Free™ Single Domain Monoclonal CD80 Products

Llama single domain antibodies (sdAbs) offer unique characteristics amenable to many applications. These sdAbs demonstrate low nanomolar binding affinity and can be used for the various applications. Note: CD80 single domain antibody should be stored in working aliquots at -20°C, stable for up to one year. As with all antibodies, care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

If you are interested in the development
of a CD80 single domain product, let us know.

Related Products

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Antigen


Cat. No.Product TypeSpeciesTissue/CellDatasheet
N/A
 
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Lysates


Cat. No.Product TypeSpeciesTissue/CellDatasheet
RF10001-06 Positive Control (Cell Lysate) Human Raji
RF10001-04 Positive Control (Tissue Lysate) Human Tonsil
RF10001-02 Negative Control (Cell Lysate) Human HEK293
 
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Slides


Cat. No.Product TypeSpeciesTissue/CellDatasheet
RF10002-04 Positive Control (Cells) Human Raji
RF10002-02 Negative Control (Cells) Human HEK293
 
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Conjugates


Cat. No.HRPBiotinCustom
RF16041 Inquire Contact Us
RF16042 Inquire Contact Us
RF16043 Inquire Contact Us
RF16044 Inquire Contact Us
RF16045 Inquire Contact Us
RF16046 Inquire Contact Us
 

Additional CD80 Antibody Products

Monoclonal antibodies are highly specific and recognize only one epitope on an antigen which generates consistent performance in quantitative detection applications regardless of production batch. Polyclonal antibodies have high affinity and recognize different epitopes on a specific antigen. Note: These antibodies can be stored at -20˚C and are stable for up to one year. Antibodies should not be exposed to prolonged high temperatures.


CD80 Monoclonal Products

Cat. No.NameApplicationsDatasheet
51-377Host Species: Mouse
Reactivity: Human
CD80 Antibody [2A2] ELISA, IF, IHC
76-040Host Species: Hamster
Reactivity: Mouse
CD80 Antibody [16-10A1] Flow, Func, IHC, IF, IP
76-042Host Species: Hamster
Reactivity: Mouse
CD80 Antibody [16-10A1] (FITC) Flow
76-045Host Species: Hamster
Reactivity: Mouse
CD80 Antibody [16-10A1] (PE) Flow
76-047Host Species: Hamster
Reactivity: Mouse
CD80 Antibody [16-10A1] (APC) Flow
76-049Host Species: Mouse
Reactivity: Rat
CD80 Antibody [3H5] (PE) Flow

CD80 Polyclonal Products

= Not Yet Determined = Negative = Fair   = Average    = Good     = Excellent
Cat. No.Antigen RangeELISAWBICCIFIHCFlowDatasheet
8679Host Species: Rabbit
Reactivity: HU, MS
60 - 110        
WB in EL4 Cell
             
42-780Host Species: Goat
Reactivity: Human
201 - 250      
WB in Lymph Node
           
61-757Host Species: Rabbit
Reactivity: Human
260 - 288      
WB in HL-60
            
Flow in HL-60 Cells
XP-5104Host Species: Rabbit
Reactivity: Mouse
1 - 288                  
XP-5104BtHost Species: Rabbit
Reactivity: Mouse
1 - 288                  

CD80 Recombinant Protein Products

Cat. No.SequenceFusion TagSpeciesTissue/CellDatasheet
90-399 Aa 35 - 237 Fc Tag Human CHO
90-400 Aa 35 - 142 Fc Tag Human CHO
90-401 Aa 37 - 245 Fc Tag Mouse CHO
92-581 Val 38 - Lys 245 C-Fc Tag Mouse Human
96-044 Val 35 - Asn 242 His Tag Human HEK293
96-045 Val 35 - Asn 242 C-Fc Tag Human HEK293
96-085 Ala 37 - Ser 160 His Tag Cynomolgus monkey HEK293

CD80 Peptide Products

Cat. No.LocationSpeciesDatasheet
42-780P A synthetic peptide corresponding to the internal region of CD80 Human
8679P 17 amino acid peptide near the amino terminus of human CD80 Human

Additional CD80 Information

 

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