IL-8 Antibody [3E4D8] Cat. No.: 32-180

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psi-iconSpecifications
HOST SPECIES:Mouse
SPECIES REACTIVITY: Human
IMMUNOGEN: Ni-NTA purified recombinant human IL-8 expressed in E.Coli. strain BL21 (DE3).
TESTED APPLICATIONS: ELISA, WB
APPLICATIONS: Western Blot:1:500 - 1,000
ELISA:1,000 - 2,000.
Determining optimal working dilutions by titration test.

psi-iconProperties
PURIFICATION:Antibody is purified by protein A affinity chromatography.
CLONALITY:Monoclonal
ISOTYPE:IgG1.kappa
CONJUGATE:Unconjugated
BUFFER:Purified antibody in PBS containing 0.03% sodium azide.
STORAGE CONDITIONS:IL-8 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:IL8
ALTERNATE NAMES:CXCL8, C-X-C motif chemokine 8, IL-8, NAF, GCP1, LECT, LUCT, NAP1, CXCL8, GCP-1, LYNAP, MDNCF, MONAP, NAP-1
ACCESSION NO.:P10145
PROTEIN GI NO.:124359
GENE ID:3576
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:Interleukin-8 (IL-8) is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
REFERENCES:1) Baggiolini M. et al. 1991. FEBS Lett. 307:97-101.
2) Mukaida N. et al. 1989. J.Immunol.143:1366-1371.

ANTIBODIES FOR RESEARCH USE ONLY.

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