IL-5 Recombinant Protein Cat. No.: 40-434

Availability: In stock

$0.00

No Image

 Price Options

$0.00
psi-iconSpecifications
SPECIES:Murine
SOURCE SPECIES:E. coli
SEQUENCE:MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG
TESTED APPLICATIONS:
BIOLOGICAL ACTIVITY: The ED50 was determined by the dose - dependent stimulation of the proliferation of human TF - 1 cells is < 2.0 ng/mL, corresponding to a specific activity of > 5 x 105 units/mg.
psi-iconProperties
PURITY:Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
PHYSICAL STATE:Lyophilized
STORAGE CONDITIONS:The lyophilized IL-5 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-5 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
psi-iconAdditional Info
ALTERNATE NAMES:EDF, TRF, IL-5, Interleukin-5, B-cell differentiation factor I
ACCESSION NO.:NP_000870.1
PROTEIN GI NO.:4504671
OFFICIAL SYMBOL:IL5
GENE ID:3567
psi-iconBackground and References
BACKGROUND:IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.