IL-23 Recombinant Protein Cat. No.: 40-559

Availability: In stock

$0.00

No Image

 Price Options

$0.00
psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:(BTI-Tn-5B1-4) High-5 Insect cells
SEQUENCE:RAVPGGSSPA WTQCQQLSQK LCTLAWSAHP LVGHMDLREE GDEETTNDVP HIQCGDGCDP QGLRDNSQFC LQRIHQGLIF YEKLLGSDIF TGEPSLLPDS PVGQLHASLL GLSQLLQPEG HHWETQQIPS LSPSQPWQRL LLRFKILRSL QAFVAVAARV FAHGAATLSP IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASISVRAQD RYYSSSWSEW ASVPCS
BIOLOGICAL ACTIVITY: Biological activity was measured by its ability to induce IL-17 secretion by mouse splenocytes. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
psi-iconProperties
PURITY:Greater than 95% by SDS-PAGE gel and HPLC analyses.
PHYSICAL STATE:Lyophilized
STORAGE CONDITIONS:The lyophilized IL-23 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-23 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-23 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
psi-iconAdditional Info
ALTERNATE NAMES:P19, SGRF, IL-23, IL-23A, IL23P19, UNQ2498/PRO5798, Interleukin-23 subunit alpha, Interleukin-23 subunit p19, IL-23 subunit alpha
ACCESSION NO.:NP_057668.1
PROTEIN GI NO.:7706702
OFFICIAL SYMBOL:IL23A
GENE ID:51561
psi-iconBackground and References
BACKGROUND:IL-23 is a proinflammatory heterodimeric protein composed of two subunits, a unique p19 subunit and a p40 subunit, which is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages, and signals though a receptor comprised of IL-23R complexed with IL-12Rβ2. IL-23 has been shown to enhance proliferation of memory T cells. It also stimulates the production of IFN-gamma in NK cells, induces IL-17 production, and drives Th17 mediated responses. Recombinant IL-23 is a 53.5 kDa heterodimeric protein consisting of two subunits, p19 (170 amino acids) and p40 (306 amino acids).*Manufactured using BTI-Tn-5B1-4 cells under license from the Boyce Thompson Institute for Plant Research, Inc.

FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.