IKB alpha Antibody Cat. No.: 18-655

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse, Pig, Rat
IMMUNOGEN: Recombinant protein of human IKB alpha
TESTED APPLICATIONS: Flow, IF, IHC, IP, WB
APPLICATIONS: WB: ,1:500 - 1:1000

IHC: ,1:50 - 1:100

IF: ,1:20 - 1:50

IP: ,1:20 - 1:50

Flow: ,1:20 - 1:50
POSITIVE CONTROL:1) Jurkat
PREDICTED MOLECULAR WEIGHT: Observed: 36kDa

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS:Store at -20˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:NFKBIA
ALTERNATE NAMES:NFKBIA, IKBA, MAD-3, NFKBI
GENE ID:4792
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

ANTIBODIES FOR RESEARCH USE ONLY.

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