IFTLD1 Antibody Cat. No.: 6447

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
IMMUNOGEN: IFLTD1 antibody was raised against an 19 amino acid synthetic peptide near the center of human IFLTD1.

The immunogen is located within amino acids 200 - 250 of IFTLD1.
TESTED APPLICATIONS: ELISA, IHC-P, WB
APPLICATIONS: IFLTD1 antibody can be used for detection of IFLTD1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.
SPECIFICITY: At least four isoforms of IFLTD1 are known to exist; this antibody will detect all but isoform 4
POSITIVE CONTROL:1) Cat. No. 1462 - Rat Lung Tissue Lysate

psi-iconProperties
PURIFICATION:IFTLD1 Antibody is affinity chromatography purified via peptide column.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:IFTLD1 Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:IFTLD1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:IFLTD1
ALTERNATE NAMES:IFTLD1 Antibody: PAS1C1, Intermediate filament tail domain-containing protein 1
ACCESSION NO.:NP_001139200
PROTEIN GI NO.:224593273
GENE ID:160492
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:IFTLD1 Antibody: The intermediate filament tail domain-containing protein (IFLTD1) was initially identified as a candidate gene for pulmonary adenoma susceptibility 1 gene in mice. Transcripts of the gene were only detected in mouse lung tissue from strains carrying the Pas1-susceptible allele. Expression of different alleles of this gene in lung cancer cell lines resulted in different levels of colony formation in in vitro colony formation assays, suggesting that allelic variants of this gene can modulate growth of human cancer cells.
REFERENCES:1) Wang M, Lemon WJ, Liu G, et al. Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines. Cancer Res. 2003; 63:3317-24.
2) Wang M, Futamura M, Wang Y, et al. Pasc1 is a candidate for the mouse pulmonary adenoma susceptibility 1 locus. Oncogene 2005; 24:1958-63.
3) Galbiati F, Pettinicchio A, Dragani TA, et al. Allelic effects of mouse Pas candidate genes in human lung cancer cell lines. Cancer Lett. 244:176-81.

ANTIBODIES FOR RESEARCH USE ONLY.

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