| HOST SPECIES: | Chicken |
| SPECIES REACTIVITY: | Virus |
| IMMUNOGEN: | 1-116 |
| TESTED APPLICATIONS: | WB |
| APPLICATIONS: | HIV-Rev antibody can be used for the detection of HIV-Rev by Western Blot. |
| PREDICTED MOLECULAR WEIGHT: | 13.1 kDa (calculated) |
Specifications| PURIFICATION: | Immunoaffinity Purified |
| CLONALITY: | Polyclonal |
| CONJUGATE: | Unconjugated |
| PHYSICAL STATE: | Liquid |
| BUFFER: | Phosphate-Buffered Saline. No preservatives added. |
| CONCENTRATION: | 1 mg/mL |
| STORAGE CONDITIONS: | HIV-Rev antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| OFFICIAL SYMBOL: | rev, p19, Human immunodeficiency virus 1, HIV |
| ALTERNATE NAMES: | Protein Rev, Anti-repression transactivator, Anti-repression transactivator protein, ART/TRS |
| ACCESSION NO.: | AAK08487.1 |
| PROTEIN GI NO.: | 12831140 |
| GENE ID: | 155908 |
| USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
| BACKGROUND: | FUNCTION: Rev appears to act post-transcriptionally to relieve negative repression of Gag and Env production. PTM: Phosphoprotein whose state of phosphorylation is mediated by a specific serine kinase activity present in the nucleus. Phosphorylated at separate regions by protein kinase CK2 and MAPK. Phosphorylation by CK2 could play a role in Rev down-regulation. SUBCELLULAR LOCATION: Nuclear; accumulates in the nucleoli. |
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