HCoV-NL63 S1 Recombinant Protein Cat. No.: 11-197

Availability: In stock

$0.00

 Price Options

$0.00
psi-iconSpecifications
SPECIES:HCoV-NL63
SOURCE SPECIES:HEK293 cells
SEQUENCE:Cys 19 - Val 717
FUSION TAG:His Tag
TESTED APPLICATIONS:WB
APPLICATIONS:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 79.5 kDa. The protein migrates as 120-140 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
psi-iconProperties
PURITY:>90% as determined by SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:79.5 kDa
PHYSICAL STATE:Lyophilized
BUFFER:PBS, pH7.4
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:Spike,S1 protein,Spike glycoprotein Subunit1,S glycoprotein Subunit1,Spike protein S1,COVID-19
psi-iconBackground and References
BACKGROUND:It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
REFERENCES:1) Wan Y, et al. J Virol. 2020. pii: JVI.00127-20.
2) Benvenuto D, et al. J Med Virol. 2020.
3) Chang CY, et al. AMB Express. 2020. 10(1):20.

FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.