Datasheet

Hantaan Virus Nucleocapsid Antibody
CATALOG NUMBER: 7689

Availability: In stock

$0.00
No Image
Product Price Options

* Required Fields

$0.00
Specifications
Properties
Additional Info
Background

Specifications

SPECIES REACTIVITY:Virus
TESTED APPLICATIONS:ELISA
APPLICATIONS:Hantaan virus nucleocapsid antibody can detect 10ng Hantaan virus nucleocapsid peptide in ELISA at 1 μg/ml.
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
PREDICTED MOLECULAR WEIGHT:N/A
IMMUNOGEN:Hantaan virus nucleocapsid antibody was raised against an 18 amino acid peptide near the amino terminus of the Hantaan virus nucleocapsid.

The immunogen is located within the first 50 amino acids of Hantaan Virus Nucleocapsid.
HOST SPECIES:Rabbit

Properties

PURIFICATION:Hantaan virus nucleocapsid antibody is affinity chromatography purified via peptide column.
PHYSICAL STATE:Liquid
BUFFER:Hantaan virus nucleocapsid antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:Hantaan virus nucleocapsid antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated

Additional Info

ALTERNATE NAMES:Hantaan Virus Nucleocapsid Antibody: Nucleoprotein, Nucleocapsid protein, Protein N
ACCESSION NO.:AFA36178
PROTEIN GI NO.:375127553
OFFICIAL SYMBOL:HTNVsSgp1
GENE ID:2943078

Background

BACKGROUND:Hantaan virus (HNTV) is the prototype virus of the genus hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA virus that is the eiological agent of Korean hemorrhagic fever (1). Infection of cultured Vero E6 cells with HNTV induced expression of the heat shock protein HSP70. A substantial fraction of HSP70 was found to be associated with the HNTV nucleocapsid (NP) (2). Vero E6 cells that overexpress HSP70 show significantly reduced levels of NP and an increased resistance to infection by HNTV (2).
REFERENCES: 1) Arikawa J, Lapenotiere HF, Iacono-Connors L, et al. Coding properties of the S and M genome segments of Sapporo rat virus: comparison to other causative agents of hemorrhagic fever with renal syndrome. Virology 1990; 176:114-25.
2) Yu L, Ye L, Zhao R, et al. HSP70 induced by Hantavirus intfection interacts with viral nucleocapsid protein and its overexpression suppresses virus infection in Vero E6 cells. Am. J. Transl. Res. 2009; 1:367-80.

For Research Use Only