Datasheet

gp120 Antibody
CATALOG NUMBER: 8677

Availability: In stock

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Specifications
Properties
Additional Info
Background

Specifications

SPECIES REACTIVITY:HIV-1
TESTED APPLICATIONS:ELISA, WB
APPLICATIONS:gp120 antibody can be used for Western blot at 1 - 2 μg/mL.
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
PREDICTED MOLECULAR WEIGHT:Predicted: 120 kDa

Observed: 120 kDa
IMMUNOGEN:gp120 antibody was raised against a peptide corresponding to 15 amino acids near the center of HIV-1 gp120.
HOST SPECIES:Rabbit

Properties

PURIFICATION:gp120 Antibody is affinity chromatography purified via peptide column.
PHYSICAL STATE:Liquid
BUFFER:gp120 Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:gp120 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated

Additional Info

ALTERNATE NAMES:gp120 Antibody: Envelope glycoprotein gp160
ACCESSION NO.:AAB05604
PROTEIN GI NO.:1465781
OFFICIAL SYMBOL:gp120
GENE ID:155971

Background

BACKGROUND:Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

For Research Use Only