Glypican 3 Recombinant Protein Cat. No.: 96-803

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psi-iconSpecifications
SPECIES:Cynomolgus monkey
SOURCE SPECIES:HEK293 cells
SEQUENCE:Gln 25 - His 559
FUSION TAG:His Tag
TESTED APPLICATIONS:ELISA, WB
APPLICATIONS:This recombinant protein can be used for E, WB. For research use only.
BIOLOGICAL ACTIVITY: Measured by its binding ability in a functional ELISA. Immobilized Human FGF basic, Tag Free at 0.5 ug/mL (100 uL/well) can bind Cynomolgus Glypican 3, His Tag with a linear range of 1-20 ng/mL (QC tested).
psi-iconProperties
PURITY:>85% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
PREDICTED MOLECULAR WEIGHT:38.1 kDa and 24.6 kDa
PHYSICAL STATE:Lyophilized
BUFFER:PBS, pH7.4
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:GPC3,OCI5,Glypican-3,GTR2-2,MXR7,DGSX,SDYS ,SGB,SGBS,SGBS1
ACCESSION NO.:XP_005594665.1
OFFICIAL SYMBOL:Glypican 3
GENE ID:102137748
psi-iconBackground and References
BACKGROUND:Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
REFERENCES:1) Davoodi J., et al., 2007, Proteomics 7:2300-2310.
2) Veugelers M., et al., 2000, Hum. Mol. Genet. 9:1321-1328.

FOR RESEARCH USE ONLY.

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