GITR Recombinant Protein Cat. No.: 97-042

Availability: In stock

$0.00

 Price Options

$0.00
psi-iconSpecifications
SPECIES:Rat
SOURCE SPECIES:HEK293 cells
SEQUENCE:Gln 20 - Lys 121
FUSION TAG:Fc Tag
TESTED APPLICATIONS:WB
APPLICATIONS:This recombinant protein can be used for WB. For research use only.
psi-iconProperties
PURITY:>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
PREDICTED MOLECULAR WEIGHT:37.2 kDa
PHYSICAL STATE:Lyophilized
BUFFER:Tris with Glycine, Arginine and NaCl, pH7.5
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:AITR,GITR,TNFRSF18,CD357
ACCESSION NO.:Q5M835
OFFICIAL SYMBOL:GITR
psi-iconBackground and References
BACKGROUND:Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
REFERENCES:1) Gurney A.L., et al., 1999, Curr. Biol. 9:215-218.
2) Park MS., et al., 2007, Yonsei Med J 48 (5): 839-46.

FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.