GHDC Antibody Cat. No.: 7061

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
IMMUNOGEN: Rabbit polyclonal GHDC antibody was raised against a 19 amino acid peptide near the amino terminus of human GHDC.

The immunogen is located within amino acids 100 - 150 of GHDC.
TESTED APPLICATIONS: ELISA, IF, WB
APPLICATIONS: GHDC antibody can be used for detection of GHDC by Western blot at 0.5 - 1 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
SPECIFICITY: Multiple isoforms are known to exist.
POSITIVE CONTROL:1) Cat. No. 1210 - HEK293 Cell Lysate
 2) Cat. No. 10-001 - Human Breast Tissue Slide
PREDICTED MOLECULAR WEIGHT: 58 kDa

psi-iconProperties
PURIFICATION:GHDC Antibody is affinity chromatography purified via peptide column.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:GHDC Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:GHDC antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:GHDC
ALTERNATE NAMES:GHDC Antibody: LGP1, D11LGP1, D11LGP1E, LGP1, GH3 domain-containing protein
ACCESSION NO.:NP_115873
PROTEIN GI NO.:14210490
GENE ID:84514
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:GHDC Antibody: GHDC, also known as LGP1, is a GH3 domain-containing protein that is highly expressed in normal mammary tissues and mammary tumors. GHDC is primarily located in the nuclear envelope. In mouse, its gene is located on chromosome 11 adjacent to the STAT3/5 locus. Little is known of the function of this protein.
REFERENCES:1) Cui Y, Li M, Walton KD, et al. The Stat3/5 locus encodes novel endoplasmic reticulum and helicase-like proteins that are preferentially expressed in normal and neoplastic mammary tissue. Genomics 2001; 78:129-34.

ANTIBODIES FOR RESEARCH USE ONLY.

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