Datasheet

GHDC Antibody
CATALOG NUMBER: 7061

Availability: In stock

$0.00
Product Price Options

* Required Fields

$0.00
Specifications
Properties
Additional Info
Background

Specifications

SPECIES REACTIVITY:Human, Mouse, Rat
TESTED APPLICATIONS:ELISA, IF, WB
APPLICATIONS:GHDC antibody can be used for detection of GHDC by Western blot at 0.5 - 1 μg/mL. For immunofluorescence start at 20 μg/mL.
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
POSITIVE CONTROL:1) Cat. No. 1210 - HEK293 Cell Lysate
 2) Cat. No. 10-001 - Human Breast Tissue Slide
PREDICTED MOLECULAR WEIGHT:58 kDa
SPECIFICITY:Multiple isoforms are known to exist.
IMMUNOGEN:Rabbit polyclonal GHDC antibody was raised against a 19 amino acid peptide near the amino terminus of human GHDC.

The immunogen is located within amino acids 100 - 150 of GHDC.
HOST SPECIES:Rabbit

Properties

PURIFICATION:GHDC Antibody is affinity chromatography purified via peptide column.
PHYSICAL STATE:Liquid
BUFFER:GHDC Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:GHDC antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated

Additional Info

ALTERNATE NAMES:GHDC Antibody: LGP1, D11LGP1, D11LGP1E, LGP1, GH3 domain-containing protein
ACCESSION NO.:NP_115873
PROTEIN GI NO.:14210490
OFFICIAL SYMBOL:GHDC
GENE ID:84514

Background

BACKGROUND:GHDC Antibody: GHDC, also known as LGP1, is a GH3 domain-containing protein that is highly expressed in normal mammary tissues and mammary tumors. GHDC is primarily located in the nuclear envelope. In mouse, its gene is located on chromosome 11 adjacent to the STAT3/5 locus. Little is known of the function of this protein.
REFERENCES: 1) Cui Y, Li M, Walton KD, et al. The Stat3/5 locus encodes novel endoplasmic reticulum and helicase-like proteins that are preferentially expressed in normal and neoplastic mammary tissue. Genomics 2001; 78:129-34.

For Research Use Only