GDI1 Antibody Cat. No.: 31-132

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human
IMMUNOGEN: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GDI1.
TESTED APPLICATIONS: ELISA, WB
APPLICATIONS: GDI1 antibody can be used for detection of GDI1 by ELISA at 1:312500. GDI1 antibody can be used for detection of GDI1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
POSITIVE CONTROL:1) Cat. No. 1211 - HepG2 Cell Lysate
PREDICTED MOLECULAR WEIGHT: 51 kDa

psi-iconProperties
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
CONCENTRATION:batch dependent
STORAGE CONDITIONS:For short periods of storage (days) store at 4˚C. For longer periods of storage, store GDI1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:GDI1
ALTERNATE NAMES:GDI1, 1A, GDIL, MRX41, MRX48, OPHN2, XAP-4, RABGD1A, RABGDIA
ACCESSION NO.:NP_001484
PROTEIN GI NO.:4503971
GENE ID:2664
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
REFERENCES:1) Papaharalambus, C., et al., (2005) J. Biol. Chem. 280 (19), 18790-18796.

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