FOXD4L1 Antibody Cat. No.: 6693

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse
IMMUNOGEN: FOXD4L1 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human FOXD4L1.

The immunogen is located within the last 50 amino acids of FOXD4L1.
TESTED APPLICATIONS: ELISA, ICC, WB
APPLICATIONS: FOXD4L1 antibody can be used for detection of FOXD4L1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry at 10 μg/ml.

Antibody validated: Western Blot in mouse samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
SPECIFICITY: This antibody is predicted to not cross-react with any FOXD4 protein family members
POSITIVE CONTROL:1) Cat. No. 1288 - A20 Cell Lysate
 2) Cat. No. 17-012 - MCF7 Cell Slide

psi-iconProperties
PURIFICATION:FOXD4L1 Antibody is affinity chromatography purified via peptide column.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:FOXD4L1 Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:FOXD4L1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:FOXD4L1
ALTERNATE NAMES:FOXD4L1 Antibody: FOXD5, bA395L14.1, Forkhead box protein D4-like 1, FOXD4-like 1
ACCESSION NO.:NP_036316
PROTEIN GI NO.:18959276
GENE ID:200350
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:FOXD4L1 Antibody: FOXD4L1, also known as FOXD5, is a member of the forkhead/winged-helix (FOX) family of transcription factors with highly conserved FOX DNA-binding domains. Members of the FOX family of transcription factors are regulators of embryogenesis and is thought to play a role in human cancer. FOXD4L1 is a forkhead transcription factor that functions as both a transcriptional activator and repressor and acts upstream of several other neural transcription factors to maintain neural fate, regulate neural plate patterning, and delay the expression of neural differentiation factors.
REFERENCES:1) Jackson BC, Carpenter C, Nebert DW, et al. Update of human and mouse forkhead box (FOX) gene families. Hum. Genomics 2010; 4:345-52.
2) Yan B, Neilson KM, and Moody SA. Microarray identification of novel downstream targets of FoxD4L1/D5, a critical component of the neural ectodermal transcriptional network. Dev. Dyn. 2010; 239:3467-80.

ANTIBODIES FOR RESEARCH USE ONLY.

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