Influenza Virus Research

Influenza virus research reagents from ProSci Inc. - antibodies and proteins 

Influenza (the flu) is a contagious respiratory illness caused by influenza viruses. It can cause mild to severe illness. Serious outcomes of flu infection can result in hospitalization or death. There are four species of influenza viruses:

  • A (IAV; genus, Alphainfluenzavirus)
  • B (IBV; Betainfluenzavirus)
  • C (ICV; Gammainfluenzavirus)
  • D (IDV; Deltainfluenzavirus)

IAV and IBV cause seasonal epidemics of disease (known as the flu season) Influenza A viruses are the only influenza viruses known to cause flu pandemics and responsible for most cases of severe illness of “the flu”.

Influenza A viruses are divided into subtypes based on the two surface proteins of the virus: hemagglutinin (H) and neuraminidase (N). One way influenza viruses change is called “antigenic drift.”, which results from mutations in the genes of the two surface proteins. The small changes that occur from antigenic drift usually produce viruses that are closely related to one another and therefore have similar antigenic properties.

Conversely “antigenic shift” causes an abrupt, major change in influenza A virus, resulting in new H and/or new H and N proteins, which can infect humans. One way shift can happen is when an influenza virus from an animal population gains the ability to infect humans. Such animal-origin viruses can contain an H or H/N combination that is so different from the same subtype in humans that most people do not have immunity to the new virus. Such a “shift” occurred in the spring of 2009 when an H1N1 virus with genes from North American Swine, Eurasian Swine, humans, and birds emerged to infect people and quickly spread, causing a pandemic. When shift happens, most people have little or no immunity against the new virus.


Influenza A Detection Sets

ProductCat. No.TargetStrainHost SpeciesTested ApplicationClonality
Avian Flu (H5N1) Protein Detection Set PSI-1808 H5N1 H5N1 Rabbit ELISA Polyclonal
Swine-Origin and Seasonal Flu H1N1 Protein PSI-1829 H1N1 H1N1 Rabbit ELISA Polyclonal


Influenza Matched Pair Antibodies

Influenza A Matched Pair Antibodies

PairCaptureDetection AntibodyBinding Protein
1 99-733 99-734 NP
2 99-733 99-735 NP

Influenza B Matched Pair Antibodies

PairCaptureDetection AntibodyBinding Protein
1 99-736 99-738 NP
2 99-736 99-739 NP


Avian Influenza A H5N1 Antibodies

ProductCat. No.TargetStrainHost SpeciesTested ApplicationsClonalityIsotype
Hemagglutinin Antibody [4F1F2] PM-4005 H5 H5N1 2004 Mouse E Monoclonal IgG3
Hemagglutinin Antibody [4H1C10] PM-4006 H5 H5N1 2004 Mouse E Monoclonal
Hemagglutinin Antibody [1E6A7] PM-4007 H5 H5N1 2004 Mouse E, WB Monoclonal IgG1
Hemagglutinin Antibody [1E7D8] PM-4008 H5 H5N1 2004 Mouse E,WB Monoclonal
Hemagglutinin Antibody [7B9B2] PM-4009 H5 H5N1 2004 Mouse E,WB Monoclonal
Hemagglutinin Antibody [4E10C10] PM-4669 H5 H5N1 2004 Mouse E,WB Monoclonal IgG1, IgG2b
Hemagglutinin Antibody [4E11E1] PM-4671 H5 H5N1 2004 Mouse E,WB Monoclonal IgG1, IgG2b
Avian Influenza Hemagglutinin Antibody 3425 H5 H5N1 2004 Rabbit E Polyclonal IgG
Avian Influenza Hemagglutinin Antibody 3427 H5 H5N1 2004 Rabbit E,WB Polyclonal IgG
Avian Influenza H5N1 Hemagglutinin (NT) Antibody 3909 H5 H5N1 2004 Goat E,WB Polyclonal IgG
Avian Influenza H5N1 Hemagglutinin (IN1) Antibody 3911 H5 H5N1 2004 Goat E,WB Polyclonal IgG
Avian Influenza H5N1 Hemagglutinin (IN2) Antibody 3913 H5 H5N1 2004 Goat E Polyclonal IgG
Avian Influenza H5N1 Hemagglutinin (IN3) Antibody 3925 H5 H5N1 2004 Goat E Polyclonal IgG
Avian Influenza Neuraminidase Antibody 3421 N1 H5N1 1959 Rabbit E Polyclonal IgG
Avian Influenza Neuraminidase Antibody 3423 N1 H5N1 1959 Rabbit E Polyclonal IgG
Avian Influenza Nonstructural Protein 1 Antibody 3915 NSP1 H5N1 2005 Rabbit E Polyclonal IgG
Avian Influenza Nonstructural Protein 2 Antibody 3917 NSP2 H5N1 2005 Rabbit E Polyclonal IgG
Avian Influenza A M2 Antibody 4333 M2 H5N1 2005 Rabbit E Polyclonal IgG


Influenza A H1N1 Antibodies

ProductCat. No.TargetStrainHost SpeciesTested ApplicationsClonalityIsotype
Seasonal H1N1 Hemagglutinin Antibody [7H12F6] PM-5533 H1 H1N1 2007 Mouse E, WB Monoclonal IgG1
Seasonal H1N1 Hemagglutinin Antibody 5231 H1 H1N1 2007 Rabbit E, WB Polyclonal IgG
Seasonal H1N1 Hemagglutinin Antibody 5235 H1 H1N1 2007 Rabbit E Polyclonal IgG
Seasonal H1N1 Hemagglutinin Antibody 5239 H1 H1N1 2007 Rabbit E Polyclonal IgG
Swine H1N1 Hemagglutinin Antibody [3E9H5] PM-5535 H1 H1N1 2007 Mouse E Monoclonal IgG2b
Swine H1N1 Hemagglutinin Antibody 5233 H1 H1N1 2009 Rabbit E, WB Polyclonal IgG
Swine H1N1 Hemagglutinin Antibody 5237 H1 H1N1 2009 Rabbit E, WB Polyclonal IgG
Swine H1N1 Hemagglutinin Antibody 5241 H1 H1N1 2009 Rabbit E Polyclonal IgG
Seasonal H1N1 Neuraminidase Antibody [10C5E11] PM-5917 N1 H1N1 2007 Mouse E Monoclonal IgG2b
Seasonal H1N1 Neuraminidase Antibody [10C5F12] PM-5919 N1 H1N1 2007 Mouse E Monoclonal IgG2b
Seasonal H1N1 Neuraminidase Antibody [6F4C8] PM-5921 N1 H1N1 2007 Mouse E Monoclonal IgG2b
H1N1 Neuraminidase Antibody 5245 N1 H1N1 2009
2006/2009
Rabbit E Polyclonal IgG
Seasonal H1N1 Neuraminidase Antibody 5247 N1 H1N1 2007 Rabbit E Polyclonal IgG
Swine H1N1 Neuraminidase Antibody 5249 N1 H1N1 2009 Rabbit E Polyclonal IgG
Seasonal H1N1 Nucleocapsid Protein Antibody 5361 NP H1N1 2009 Rabbit E Polyclonal IgG
Swine H1N1 Nucleocapsid Protein Antibody 5715 NP H1N1 2009 Rabbit E, IF Polyclonal IgG
Seasonal H1N1 Nonstructural Protein 1 Antibody 5357 NSP1 H1N1 2005 Rabbit E Polyclonal IgG
Swine H1N1 Nonstructural Protein 1 Antibody 5359 NSP1 H1N1 2009 Rabbit E Polyclonal IgG
Influenza A Virus (H1N1) Antibody 35-281 H1N1 H1N1 90/77 Goat WB, IHC Polyclonal
Influenza A Virus (H1N1) Antibody (FITC) 35-282 H1N1 H1N1 90/77 Goat WB, IHC Polyclonal
Influenza A Virus (H1N1) Antibody (HRP) 35-283 H1N1 H1N1 90/77 Goat WB, IHC Polyclonal
Influenza A Virus (H1N1) Antibody (Biotin) 35-284 H1N1 H1N1 90/77 Goat WB, IHC Polyclonal


Influenza A H3N2 Antibodies

ProductCat. No.TargetStrainHost SpeciesTested ApplicationsClonality
Influenza A Virus (H3N2) Antibody 35-285 H3N2 H3N2 2017 Goat WB Polyclonal
Influenza A Virus (H3N2) Antibody (FITC) 35-286 H3N2 H3N2 2017 Goat WB Polyclonal
Influenza A Virus (H3N2) Antibody (HRP) 35-287 H3N2 H3N2 2017 Goat WB Polyclonal
Influenza A Virus (H3N2) Antibody (Biotin) 35-288 H3N2 H3N2 2017 Goat WB Polyclonal
Influenza A Virus - Matrix Antibody 35-277 H3N2 H3N2 1982 Goat WB Polyclonal
Influenza A Virus - Matrix Antibody (FITC) 35-278 H3N2 H3N2 1982 Goat WB Polyclonal
Influenza A Virus - Matrix Antibody (HRP) 35-279 H3N2 H3N2 1982 Goat WB Polyclonal
Influenza A Virus - Matrix Antibody (Biotin) 35-280 H3N2 H3N2 1982 Goat WB Polyclonal


Avian Influenza A H7N9 Antibodies

ProductCat. No.TargetStrainHost SpeciesTested ApplicationsClonalityIsotype
Avian Influenza A H7N9 Hemagglutinin Antibody 7821 H7 H7N9 2013 Rabbit E Polyclonal IgG
Avian Influenza A H7N9 Hemagglutinin Antibody 7823 H7 H7N9 2013 Rabbit E Polyclonal IgG
Avian Influenza A H7N9 Hemagglutinin Antibody 7825 H7 H7N9 2013 Rabbit E Polyclonal IgG
Avian Influenza A H7N9 Neuraminidase Antibody 7827 N9 H7N9 2013 Rabbit E Polyclonal IgG
Avian Influenza A H7N9 Neuraminidase Antibody 7831 N9 H7N9 2013 Rabbit E Polyclonal IgG
Avian Influenza A H7N9 Neuraminidase Antibody 7833 N9 H7N9 2013 Rabbit E Polyclonal IgG


Influenza A Antibodies

ProductCat. No.TargetStrainHost SpeciesTested ApplicationsClonalityIsotype
Influenza A, Nucleoprotein Antibody [FluA-NP 2C9] 99-733 NP Mouse IHC-Fr, Flow, IP, Activity Monoclonal IgG2a
Influenza A, Nucleoprotein Antibody [FluA-NP 4F1] 99-734 NP Mouse Flow Monoclonal IgG1
Influenza A, Nucleoprotein Antibody [FluA-NP 4F1] (HRP) 99-735 NP Mouse Flow Monoclonal IgG1
Influenza A, Matrix Protein Antibody [FluAc] 99-731 M Mouse Flow Monoclonal IgG2b
Influenza A, Matrix Protein Antibody [FluAc] (HRP) 99-732 M Mouse IHC-Fr, Flow Monoclonal IgG2b
Influenza A Virus Antibody [1331] 35-481 NP Most Mouse E, ICC, IF Monoclonal IgG2a
Influenza A Virus Antibody [1333] (FITC) 35-482 NP Most Mouse E, ICC, IF Monoclonal IgG2a
Influenza A Virus Antibody [1341] 35-483 NP All Mouse E, ICC, IF Monoclonal IgG2a
Influenza A Virus Antibody [1343] (FITC) 35-484 NP All Mouse E, ICC, IF Monoclonal IgG2a
Influenza A Virus Antibody [1361] 35-485 NP All Mouse E Monoclonal IgG1
Influenza A Virus Antibody [1371] 35-486 NP All Mouse E Monoclonal IgG1
Influenza A Virus Antibody [1381] 35-487 NP All Mouse E Monoclonal IgG1


Influenza B Antibodies

ProductCat. No.TargetStrainHost SpeciesTested ApplicationsClonalityIsotype
Influenza B, Nucleoprotein Antibody [3D7] 99-736 NP Mouse Flow Monoclonal IgG2b
Influenza B, Nucleoprotein Antibody [3D7] (HRP) 99-737 NP Mouse IHC-Fr, Flow, IP Monoclonal IgG2b
Influenza B, Nucleoprotein Antibody [1H7a] 99-738 NP Mouse IHC-Fr, Flow Monoclonal IgG1
Influenza B, Nucleoprotein Antibody [1H7a] (HRP) 99-739 NP Mouse IHC-Fr, Flow, IP, Activity Monoclonal IgG1
Influenza B Virus Antibody 35-289 Influenza B Yamagata Goat E, WB, IF Polyclonal
Influenza B Virus Antibody (FITC) 35-290 Influenza B Yamagata Goat E, WB, IF Polyclonal
Influenza B Virus Antibody (HRP) 35-291 Influenza B Yamagata Goat E, WB, IF Polyclonal
Influenza B Virus Antibody (Biotin) 35-292 Influenza B Yamagata Goat E, WB, IF Polyclonal
Influenza B Virus Antibody [1131] 35-462 NP Mouse IF Monoclonal IgG2b
Influenza B Virus Antibody [1133] (FITC) 35-463 NP Mouse IF Monoclonal IgG2b
Influenza B Virus Antibody [1161] 35-466 NP Mouse E, IF Monoclonal IgG2b
Influenza B Virus Antibody [1171] 35-467 NP Mouse E, IF Monoclonal IgG2b
Influenza B Virus Antibody [1181] 35-468 NP Mouse E, IF Monoclonal IgG2b


Parainfluenza Antibodies

ProductCat. No.Host SpeciesTested ApplicationsClonalityIsotype
Parainfluenza Virus, Type 1 Antibody 35-329 Goat WB Polyclonal
Parainfluenza Virus, Type 1 Antibody (HRP) 35-331 Goat WB Polyclonal
Parainfluenza Virus, Type 1 Antibody (Biotin) 35-332 Goat WB Polyclonal
Parainfluenza Virus, Type 3 Antibody 35-333 Goat WB Polyclonal
Parainfluenza Virus, Type 3 Antibody (FITC) 35-334 Goat WB Polyclonal
Parainfluenza Virus, Type 3 Antibody (HRP) 35-335 Goat WB Polyclonal
Parainfluenza Virus, Type 3 Antibody (Biotin) 35-336 Goat WB Polyclonal
Parainfluenza Virus Antibody [1221] 35-469 Mouse E, IF Monoclonal IgG2b
Parainfluenza Virus Antibody [1224] 35-470 Mouse E, IF Monoclonal IgG2a
Parainfluenza Virus Antibody [1226] 35-471 Mouse E, IF Monoclonal IgG2a
Parainfluenza Virus Antibody [1231] 35-472 Mouse IF Monoclonal IgG2b
Parainfluenza Virus Antibody [1233] (FITC) 35-473 Mouse IF Monoclonal IgG2b
Parainfluenza Virus Antibody [1241] 35-474 Mouse IF Monoclonal IgG2a
Parainfluenza Virus Antibody [1243] (FITC) 35-475 Mouse IF Monoclonal IgG2a
Parainfluenza Virus Antibody [1254] 35-476 Mouse E, IF Monoclonal IgG1
Parainfluenza Virus Antibody [1256] 35-477 Mouse E, IF Monoclonal IgG2a
Parainfluenza Virus Antibody [1259] (FITC) 35-478 Mouse E, IF Monoclonal IgG2a
Parainfluenza Virus Antibody [1258] 35-479 Mouse E, IF Monoclonal IgG2a


Influenza Recombinant Proteins

ProductCat. No.SourceFusion TagSequenceStrain
Hemagglutinin Recombinant Protein 95-101 E. coli His Tag and StrepII Tag Asp 17-Gln 338 H5N1
Influenza A Hemagglutinin Recombinant Protein 96-374 HEK293 cells His Tag Asp 17-Gln 338, Leu 341-Asp 523 H7N9
Influenza A Hemagglutinin Recombinant Protein 96-377 HEK293 cells C-Fc Tag Asp 19-Asp 523 H7N9
Hemagglutinin (HA) Recombinant Protein 97-055 HEK293 cells His Tag Asp 19-Arg 338 H9N2
Hemagglutinin (HA) Recombinant Protein 97-056 HEK293 cells His Tag Asp 19-Lys 523 H9N2
Hemagglutinin (HA) Recombinant Protein 97-057 HEK293 cells His Tag Asp 17-Gln 531 H5N1
Influenza A virus Neuraminidase Recombinant Protein 96-372 HEK293 cells His Tag His 36-Lys 449 H5N1
NAD Nucleotidase H. influenzae Recombinant Protein 90-368 E. coli Tag Free Glu 27-Lys 603