FasL, Soluble Recombinant Protein Cat. No.: 90-215

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psi-iconSpecifications
SPECIES:Human, Mouse
SOURCE SPECIES:HEK293 cells
SEQUENCE:The extracellular domain of human FasL (aa 103-281) is fused at the N-terminus to a DDDDK-tag.
FUSION TAG:DDDDK Tag
TESTED APPLICATIONS:
APPLICATIONS:This recombinant proteins is for research use only.
BIOLOGICAL ACTIVITY: Induces apoptosis of human Jurkat T cells at a concentration of <1ng/ml in the presence of 0.1 to 1ug/ml TNF Ligands Enhancer (Prod. No. AG-35B-0001). In the absence of TNF Ligands Enhancer, FasL is working at 50-100 fold higher concentrations.
psi-iconProperties
PURITY:>95% (SDS-PAGE).

Endotoxin level is less than 0.05EU/ μg purified protein (LAL test; Lonza).
PHYSICAL STATE:Lyophilized
BUFFER:Contains PBS. Reconstitute with 100 μl sterile water.
CONCENTRATION:0.1mg/ml after reconstitution.
STORAGE CONDITIONS:Stable for at least 6 months after receipt when stored at -20˚C.
psi-iconAdditional Info
ALTERNATE NAMES:APO-1L, CD95L, CD178, TNFSF6, Fas Ligand
ACCESSION NO.:P48023
PROTEIN GI NO.:4557329
OFFICIAL SYMBOL:FASLG
GENE ID:356
psi-iconBackground and References
BACKGROUND:FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. Is involved in cytotoxic T cell mediated apoptosis and in T cell development.

FOR RESEARCH USE ONLY.

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