ERLIN1 Antibody Cat. No.: 56-838

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human
HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse
IMMUNOGEN: This ERLIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244-273 amino acids from the Central region of human ERLIN1.
TESTED APPLICATIONS: IHC-P, WB
APPLICATIONS: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
PREDICTED MOLECULAR WEIGHT: 39 kDa

psi-iconProperties
PURIFICATION:This antibody is purified through a protein A column, followed by peptide affinity purification.
CLONALITY:Polyclonal
ISOTYPE:Rabbit Ig
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS with 0.09% (W/V) sodium azide.
CONCENTRATION:batch dependent
STORAGE CONDITIONS:Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:ERLIN1
ALTERNATE NAMES:Erlin-1, Endoplasmic reticulum lipid raft-associated protein 1, Protein KE04, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1, SPFH domain-containing protein 1, ERLIN1, C10orf69, KE04, KEO4, SPFH1
ACCESSION NO.:O75477
GENE ID:10613
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs).
REFERENCES:1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
2) Martins-de-Souza, D., et al.Psychiatr Res (2010) In press :
3) Wang, Y., et al. Biochim. Biophys. Acta 1793(11):1710-1718(2009)
4) Pearce, M.M., et al. J. Biol. Chem. 284(16):10433-10445(2009)

ANTIBODIES FOR RESEARCH USE ONLY.

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