EIF4H Antibody Cat. No.: 56-537

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human
HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse
IMMUNOGEN: This EIF4H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from the Central region of human EIF4H.
TESTED APPLICATIONS: IHC-P, WB
APPLICATIONS: For IHC-P starting dilution is: 1:10~50

For WB starting dilution is: 1:1000
PREDICTED MOLECULAR WEIGHT: 27 kDa

psi-iconProperties
PURIFICATION:This antibody is purified through a protein A column, followed by peptide affinity purification.
CLONALITY:Polyclonal
ISOTYPE:Rabbit Ig
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS with 0.09% (W/V) sodium azide.
CONCENTRATION:batch dependent
STORAGE CONDITIONS:Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:EIF4H
ALTERNATE NAMES:Eukaryotic translation initiation factor 4H, eIF-4H, Williams-Beuren syndrome chromosomal region 1 protein, EIF4H, KIAA0038, WBSCR1, WSCR1
ACCESSION NO.:Q15056
PROTEIN GI NO.:18276665
GENE ID:7458
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.
REFERENCES:1) Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
2) Zhu, X., et al. Genet. Epidemiol. 34(2):171-187(2010)
3) Mokas, S., et al. Mol. Biol. Cell 20(11):2673-2683(2009)
4) Marintchev, A., et al. Cell 136(3):447-460(2009)

ANTIBODIES FOR RESEARCH USE ONLY.

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