EIF4E-Binding Protein 2 Recombinant Protein Cat. No.: 92-025

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:E. coli
SEQUENCE:Met1-Ile120
FUSION TAG:N-6 His tag
TESTED APPLICATIONS:
APPLICATIONS:This recombinant protein can be used for biological assays. For research use only.
psi-iconProperties
PURITY:Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
PREDICTED MOLECULAR WEIGHT:15.1 kD
PHYSICAL STATE:Lyophilized
BUFFER:Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
STORAGE CONDITIONS:Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
psi-iconAdditional Info
ALTERNATE NAMES:Eukaryotic Translation Initiation Factor 4E-Binding Protein 2, 4E-BP2, eIF4E-Binding Protein 2, EIF4EBP2
ACCESSION NO.:Q13542
PROTEIN GI NO.:767904139
OFFICIAL SYMBOL:EIF4EBP2
GENE ID:1979
psi-iconBackground and References
BACKGROUND:Eukaryotic Translation Initiation Factor 4E-Binding Protein 2 (EIF4EBP2) is a member of the Eukaryotic Translation Initiation Factor 4E Binding Protein Family. EIF4EBP2 regulates eIF4E activity by preventing its assembly into the eIF4F complex, mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway. This regulation of is associated to cell proliferation, cell differentiation and viral infection. Phosphorylated EIF4EBP2 on serine and threonine residues in response to insulin, EGF and PDGF.

FOR RESEARCH USE ONLY.

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