EDAR Antibody Cat. No.: 15-374

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Mouse, Rat
IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 27-187 of human EDAR (NP_071731.1).
TESTED APPLICATIONS: IF, WB
APPLICATIONS: WB: ,1:500 - 1:2000

IF: ,1:50 - 1:200
POSITIVE CONTROL:1) Mouse lung
 2) Mouse liver
PREDICTED MOLECULAR WEIGHT: Observed: 48kDa

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS:Store at -20˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:EDAR
ALTERNATE NAMES:EDAR, DL, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1, ECTD10A, ECTD10B
GENE ID:10913
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

ANTIBODIES FOR RESEARCH USE ONLY.

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