DR3 / TNFRSF25 Recombinant Protein Cat. No.: 96-794

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psi-iconSpecifications
SPECIES:Cynomolgus, Rhesus macaque
SOURCE SPECIES:HEK293 cells
SEQUENCE:Gln 20 - Gly 203
FUSION TAG:Fc Tag
TESTED APPLICATIONS:WB
APPLICATIONS:This recombinant protein can be used for WB. For research use only.
psi-iconProperties
PURITY:>90% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
PREDICTED MOLECULAR WEIGHT:46.3 kDa
PHYSICAL STATE:Lyophilized
BUFFER:Tris with Glycine, Arginine and NaCl, pH7.5
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:TNFRSF25,DR3,APO3,DDR3,TNFRSF12,WSL,WSL1
ACCESSION NO.:G7NTB5
OFFICIAL SYMBOL:DR3 / TNFRSF25
psi-iconBackground and References
BACKGROUND:Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.
REFERENCES:1) Kitson J., et al., 1996, Nature 384:372-375.
2) Bodmer J.-L., et al., 1997, Immunity 6:79-88.
3) Marsters S.A., et al., 1996, Curr. Biol. 6:1669-1676.

FOR RESEARCH USE ONLY.

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