DDX23 Antibody Cat. No.: 28-488

Availability: In stock

$0.00

 Price Options

$0.00
psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Dog, Human, Mouse, Rat, Zebrafish
IMMUNOGEN: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DDX23.
TESTED APPLICATIONS: ELISA, WB
APPLICATIONS: DDX23 antibody can be used for detection of DDX23 by ELISA at 1:1562500. DDX23 antibody can be used for detection of DDX23 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
POSITIVE CONTROL:1) Cat. No. 1211 - HepG2 Cell Lysate
PREDICTED MOLECULAR WEIGHT: 90 kDa

psi-iconProperties
PURIFICATION:Antibody is purified by protein A chromatography method.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
CONCENTRATION:batch dependent
STORAGE CONDITIONS:For short periods of storage (days) store at 4˚C. For longer periods of storage, store DDX23 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:DDX23
ALTERNATE NAMES:DDX23, prp28, PRPF28, U5-100K, SNRNP100, U5-100KD
ACCESSION NO.:NP_004809
PROTEIN GI NO.:41327771
GENE ID:9416
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.
REFERENCES:1) Teigelkamp, S., et al., (1997) RNA 3 (11), 1313-1326.

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.