DAZAP2 Antibody Cat. No.: 64-216

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human
IMMUNOGEN: This DAZAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the C-terminal region of human DAZAP2.
TESTED APPLICATIONS: IHC-P, WB
APPLICATIONS: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
PREDICTED MOLECULAR WEIGHT: 17 kDa

psi-iconProperties
PURIFICATION:This antibody is purified through a protein A column, followed by peptide affinity purification.
CLONALITY:Polyclonal
ISOTYPE:Rabbit Ig
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS with 0.09% (W/V) sodium azide.
CONCENTRATION:batch dependent
STORAGE CONDITIONS:Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:DAZAP2
ALTERNATE NAMES:DAZ-associated protein 2, Deleted in azoospermia-associated protein 2, DAZAP2, KIAA0058
ACCESSION NO.:Q15038
PROTEIN GI NO.:44887865
GENE ID:9802
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:DAZAP2 encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma.
REFERENCES:1) Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
2) Kim, J.E., et al. Mol. Cell. Biol. 28(2):803-813(2008)
3) Shi, Y.W., et al. Chin. Med. J. 120(19):1659-1665(2007)

ANTIBODIES FOR RESEARCH USE ONLY.

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