CYP11B1 Antibody Cat. No.: 15-847

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human
IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP11B1 (NP_000488.3).
TESTED APPLICATIONS: IF
APPLICATIONS: IF: ,1:50 - 1:200

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS:Store at -20˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:CYP11B1
ALTERNATE NAMES:CPN1, CYP11B, FHI, P450C11, cytochrome P450 11B1, mitochondrial, CYPXIB1, cytochrome P-450c11, cytochrome P45family 11, subfamily B, polypeptide 1, cytochrome P45subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1, cytochrome P450C11, cytochrome p450 XIB1, steroid 11-beta-hydroxylase, steroid 11-beta-monooxygenase
GENE ID:1584
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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