CYLD Antibody Cat. No.: 45-444

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psi-iconSpecifications
HOST SPECIES:Goat
SPECIES REACTIVITY: Mouse, Rat
IMMUNOGEN: The immunogen for this antibody is: C-DSQQSKSKNPWYIDE
TESTED APPLICATIONS: ELISA, IHC, WB
APPLICATIONS: Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Approx 125kDa band observed in Rat Brain lysates (calculated MW of 107kDa according to mouse NP_775545.1). Recommended concentration: 0.5-1.5ug/ml.Immunohistochemistry:Paraffin embedded Mouse Brain. Recommended concentration: 5ug/ml.
POSITIVE CONTROL:1) Cat. No. 1463 - Rat Brain Tissue Lysate

psi-iconProperties
PURIFICATION:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
CONCENTRATION:500 ug/mL
STORAGE CONDITIONS:Aliquot and store at -20˚C. Minimize freezing and thawing.

psi-iconAdditional Info
OFFICIAL SYMBOL:Cyld
ALTERNATE NAMES:CYLD, cylindromatosis (turban tumor syndrome) , 2010013M14Rik, 2900009M21Rik, C130039D01Rik, CDMT, CYLD1, EAC, mKIAA0849, ubiquitin carboxyl-terminal hydrolase CYLD
ACCESSION NO.:NP_775545.1
PROTEIN GI NO.:27734060
GENE ID:74256 (mouse); 312937 (rat);
psi-iconBackground and References
REFERENCES:1) Massoumi R, Chmielarska K, Hennecke K, Pfeifer A, Fassler R. Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. Cell. 2006 May 19;125(4):665-77.

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