CXCR4 Antibody Cat. No.: XW-7735

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psi-iconSpecifications
HOST SPECIES:Chicken
SPECIES REACTIVITY: Bovine, Human, Mouse, Rat
IMMUNOGEN: 6-41
TESTED APPLICATIONS: WB
APPLICATIONS: C-X-C chemokine receptor type 4 antibody can be used for the detection of C-X-C chemokine receptor type 4 by Western Blot.
PREDICTED MOLECULAR WEIGHT: 39.7 kDa (calculated)

psi-iconProperties
PURIFICATION:Immunoaffinity Purified
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Phosphate-Buffered Saline. No preservatives added.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:CXCR4 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:CXCR4
ALTERNATE NAMES:C-X-C chemokine receptor type 4, FB22, CXC-R4, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LESTR, NPY3R, NPYRL, HSY3RR, NPYY3R, D2S201E, CXC chemokine receptor type 4, CXCR-4, Stromal cell-derived factor 1 receptor, SDF-1 receptor, Fusin, Leukocyte-derived seven transmembrane domain receptor, CD184 antigen
ACCESSION NO.:NP_003458.1
PROTEIN GI NO.:4503175
GENE ID:7852
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:FUNCTION: Receptor for the C-X-C chemokine SDF-1. Transduces a signal by increasing the intracellular calcium ions level. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodelling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a primary receptor for some HIV-2 isolates and as a coreceptor with CD4 for HIV-1 X4 viruses (lymphocyte-tropic HIV-1 viruses, also called syncytium-inducing (SI) strains). Promotes Env-mediated fusion of the virus.

ANTIBODIES FOR RESEARCH USE ONLY.

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