CX3CL1 Recombinant Protein Cat. No.: 91-417

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:Human Cells
SEQUENCE:Gln25-Arg339
FUSION TAG:C-6 His tag
TESTED APPLICATIONS:
APPLICATIONS:This recombinant protein can be used for biological assays. For research use only.
psi-iconProperties
PURITY:Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
PREDICTED MOLECULAR WEIGHT:34.36 kD
PHYSICAL STATE:Lyophilized
BUFFER:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
STORAGE CONDITIONS:Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
psi-iconAdditional Info
ALTERNATE NAMES:Fractalkine, C-X3-C Motif Chemokine 1, CX3C Membrane-Anchored Chemokine, Neurotactin, Small-Inducible Cytokine D1, CX3CL1, FKN, NTT, SCYD1
ACCESSION NO.:P78423
OFFICIAL SYMBOL:CX3CL1
GENE ID:6376
psi-iconBackground and References
BACKGROUND:Human Fractalkine (CX3CL1) is a member of the CX3C family of chemokines. Human Fractalkine contains both chemokine and mucin domain. The soluble form of Fractalkine is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane bound form of Fractalkine promotes leukocytes adhesion to endothelial cells. Fractalkine regulates leukocyte adhesion and migration processes at the endothelium and binds to CX3CR1. Natural Human Fractalkine is produced as a long protein (373-amino acid). The mucin-like stalk permits it to bind to the cell surface.

FOR RESEARCH USE ONLY.

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