Single Domain Antibody Services

Throughout all five phases (from immunization to production), single domain integrity is ensured with ProSci’s unwavering commitment to customer satisfaction and multiple quality control checks. If your clinical application calls for single domain antibodies (VHH antibodies), purchase ProSci single domain antibodies with confidence! We’ve earned the trust from both private and public research sectors, working in a variety of research applications – therapeutic, general research, diagnostic, pharmaceutical and many more.

Single Domain Project Quote Form


Select a Package

Help me pick my process.




Help me choose a package.

Phase Procedure Detailed Procedure Select Phase
Phase I Immunization
  • Immunization of 1 llama on standard 12-week protocol
  • ELISA using each bleed screened against antigen
  Add Phase 1
Phase II PBMC Isolation
  • PBMC's isolated and preserved from 100mL blood collected at weeks 8 and 12
  Add Phase 2
Phase III Library Construction
  • SDAb library construction from Phase II PBMC's (customer's choice of bleed, 2 or 3
  Add Phase 3
Phase IV Library Screening
  • Panning of phage library against antigen
  • Screening by direct ELISA
  • Selection and sequencing of binders
  • Relative affinity determination by ELISA
  • 100 µg of up to 6 final clones (clones from distinct sequence families)
  • Additional screening data (if requested; additional charge)
  Add Phase 4
Phase V
  • Expression and purification of additional quantities of antibody
  • Please note that this Phase is optional and will be excluded
    from the "Add All Phases" option by default
  Add Phase 5
Phases I ~ IV
  • This selection will add Phases 1 ~ IV to your order
  • You may choose to add Phase V at any point
Add All Phases


Select Add-Ons

Add-On Services
Additional Single Domain Antibodies (Per Antibody) Qty:  

Additional ELISA Screening Qty:  
Custom Screening of Phage Display Library Western Blot Screening

Immunocytochemistry Screening


Select Shipping Options

Shipping Options
Cold Shipping Materials & Handling Fee
Ship after each bleed - Initial 12 weeks
Ship after 1st and 3rd bleed - Initial 12 weeks
Ship after 3rd bleed - Initial 12 weeks
ProSci FedEx Account
My FedEx Account

Billing Information

Address Line 1*
Address Line 2
City, State, Zip*


* Indicates required fields

Once form is created, please make sure to send PDF copy to ProSci at or fax it at +1 (858) 513-2692.

Additional Antibody Services

Additional services distinguish us from our competitors: pre-screening samples for animals allow you to test and select hosts with minimal background, spleen removal services are available for work with smaller species, and a test bleed will supply you with enough serum to determine your satisfaction with the project before it continues.
See more in the Additional Antibody Services page.


Contact Us

I am NOT interested in receiving promotions, discounts or news.