CTXB Recombinant Protein Cat. No.: 97-073

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psi-iconSpecifications
SPECIES:Vibrio cholerae serotype O1
SOURCE SPECIES:HEK293 cells
SEQUENCE:Thr 22 - Asn 124
FUSION TAG:His Tag
TESTED APPLICATIONS:WB
APPLICATIONS:This recombinant protein can be used for WB. For research use only.
psi-iconProperties
PURITY:>92% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
PREDICTED MOLECULAR WEIGHT:13.5 kDa
PHYSICAL STATE:Lyophilized
BUFFER:PBS, pH7.4
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:CTXB,TOXB
ACCESSION NO.:P01556
OFFICIAL SYMBOL:CTXB
GENE ID:2613962
psi-iconBackground and References
BACKGROUND:Cholera enterotoxin subunit B (CTXB) is also known as cholera enterotoxin B chain, cholera enterotoxin gamma chain and choleragenoid. Vibrio cholerae O1 exists as two major serotypes, Inaba and Ogawa, which are associated with the O antigen of the lipopolysaccharide and are capable of unequal reciprocal interconversion. The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. CTXB can bind five GM1 gangliosides. Also, it has no toxic activity by itself.
REFERENCES:1) Lockman H., et al., 1983, J. Biol. Chem. 258:13722-13726.
2) Fujinaga Y., et al., 2003, Mol. Biol. Cell 14:4783-4793.

FOR RESEARCH USE ONLY.

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