CD86 Antibody [2D10] Cat. No.: 99-099

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psi-iconSpecifications
HOST SPECIES:Rat
SPECIES REACTIVITY: Mouse
IMMUNOGEN: Mouse B cell lymphoma cell line 5C2
TESTED APPLICATIONS: Flow, IHC-Fr, IHC-P, IP
APPLICATIONS: CD86 Antibody [2D10] for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, separation, CMCD, and blocking assays.
SPECIFICITY: CD86

psi-iconProperties
CLONALITY:Monoclonal
ISOTYPE:IgG2b
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS
CONCENTRATION:0.5 mg/mL
STORAGE CONDITIONS:Store vial at -20˚C

psi-iconAdditional Info
OFFICIAL SYMBOL:Cd86
ALTERNATE NAMES:B7-2, B70, Ly-58
ACCESSION NO.:P42082
GENE ID:12524
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:CD86 (B7-2) is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80 (B7-1), CD86 participates in T cell costimulation via interaction with CD28 and CD152 (CTLA-4). It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes, and dendritic cells. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.

ANTIBODIES FOR RESEARCH USE ONLY.

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