CD69 Antibody [H1.2F3] Cat. No.: 76-819

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psi-iconSpecifications
HOST SPECIES:Hamster
SPECIES REACTIVITY: Mouse
TESTED APPLICATIONS: Flow, Func
SPECIFICITY: The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM).

psi-iconProperties
PURIFICATION:The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
CLONALITY:Monoclonal
ISOTYPE:Armenian Hamster IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:liquid
BUFFER:Phosphate-buffered aqueous solution, ph7.2.
CONCENTRATION:batch dependent
STORAGE CONDITIONS:The product should be stored undiluted at 4˚C . Do not freeze.

psi-iconAdditional Info
OFFICIAL SYMBOL:Cd69
ALTERNATE NAMES:AIM, VEA, AI452015, 5830438K24Rik, Cd69
GENE ID:12515
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
REFERENCES:1) Marzio, R., Jirillo, E., Ransijn, A., Mauel, J., Corradin, S. B. (1997). Expression and function of the early activation antigen CD69 in murine macrophages.Journal of leukocyte biology,62(3), 349-355.
2) Yokoyama, W. M., Koning, F., Kehn, P. J., Pereira, G. M., Stingl, G., Coligan, J. E., Shevach, E. M. (1988). Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation.The Journal of Immunology,141(2), 369-376.
3) Sobel, E. S., Yokoyama, W. M., Shevach, E. M., Eisenberg, R. A., Cohen, P. L. (1993). Aberrant expression of the very early activation antigen on MRL/Mp-lpr/lpr lymphocytes.The Journal of Immunology,150(2), 673-682.

ANTIBODIES FOR RESEARCH USE ONLY.

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