Datasheet

CD66b Antibody [G10F5] (PE)
CATALOG NUMBER: 76-594

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Specifications
Properties
Additional Info
Background

Specifications

SPECIES REACTIVITY:Human
TESTED APPLICATIONS:Flow
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
SPECIFICITY:The G10F5 monoclonal antibody specifically reacts with human CD66b, a 100kDa glycosylphosphatidylinositol (GPI) linked protein in the granulocyte-specific activation family.
HOST SPECIES:Mouse

Properties

PURIFICATION:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
PHYSICAL STATE:liquid
BUFFER:Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
CONCENTRATION:batch dependent
STORAGE CONDITIONS:The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
CLONALITY:Monoclonal
ISOTYPE:Mouse IgM, kappa
CONJUGATE:PE

Additional Info

ALTERNATE NAMES:CD67, CGM6, CD66b, NCA-95, CEACAM8
OFFICIAL SYMBOL:CEACAM8
GENE ID:1088

Background

BACKGROUND:The G10F5 monoclonal antibody specifically reacts with human CD66b, a 100kDa glycosylphosphatidylinositol (GPI) linked protein in the granulocyte-specific activation family. CD66b is expressed on granulocytes, neutrophils, and eosinophils. It is reported that this molecule plays a role in regulating neutrophil activation and cellular adhesion. It was previously classified as CD67, but renamed CD66b in the Fifth HLDA Workshop.
REFERENCES: 1) Knapp W(1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
2) Azuma, M., Ito, D., Yagita, H., Okumura, K., Phillips, J. H., Lanier, L. L., Somoza, C. (1993). B70 antigen is a second ligand for CTLA-4 and CD28.Nature,366(6450), 76-79.
3) Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.

For Research Use Only