CD51 Antibody [13C2] (FITC) Cat. No.: 99-551

Availability: In stock

$0.00

No Image

 Price Options

$0.00
psi-iconSpecifications
HOST SPECIES:Mouse
SPECIES REACTIVITY: African green monkey, Bovine, Human, Rabbit
IMMUNOGEN: Cell suspension containing osteoclasts from osteoclastomas
TESTED APPLICATIONS: Flow, IHC-Fr, IP
APPLICATIONS: CD51 Antibody [13C2] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
SPECIFICITY: CD51

psi-iconProperties
CLONALITY:Monoclonal
ISOTYPE:IgG1
CONJUGATE:FITC
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS/NaN3
CONCENTRATION:Lot specific
STORAGE CONDITIONS:Store vial at 2-8˚C

psi-iconAdditional Info
OFFICIAL SYMBOL:ITGAV
ALTERNATE NAMES:Integrin alphaV, vitronectin receptor, VNR-alpha chain
ACCESSION NO.:P06756
GENE ID:3685
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:CD51 represents the integrin alphaV chain that associates with integrin beta3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils, and platelets. CD51 is the most promiscuous integrin alpha subunit as it can form heterodimers with the beta1 (CD29), beta3 (CD61), beta5, beta6 and beta8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.