This recombinant protein can be used for WB. For research use only.
BIOLOGICAL ACTIVITY:
Measured by its binding ability in a functional ELISA. Immobilized Human CD48, His Tag at 5μg/mL (100 μL/well) can bind Human 2B4, Fc Tag with a linear range of 0.31-2.5 μg/mL.
Properties
PURITY:
>95% as determined by SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:
23.2 kDa
PHYSICAL STATE:
Lyophilized
BUFFER:
PBS, pH7.4
STORAGE CONDITIONS:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.
REFERENCES:
1) Korinek V., et al., 1991, Immunogenetics 33:108-112.
2) Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.
Specifications
