CD4 Antibody [RFT4] (Cy5) Cat. No.: 99-431

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psi-iconSpecifications
HOST SPECIES:Mouse
SPECIES REACTIVITY: Human
IMMUNOGEN: Thymocytes and E-rosetted lymphocytes
TESTED APPLICATIONS: Flow
APPLICATIONS: CD4 Antibody [RFT4] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
SPECIFICITY: CD4

psi-iconProperties
CLONALITY:Monoclonal
ISOTYPE:IgG1
CONJUGATE:Cy5
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS/NaN3
CONCENTRATION:Lot specific
STORAGE CONDITIONS:Store vial at 2-8˚C

psi-iconAdditional Info
OFFICIAL SYMBOL:CD4
ALTERNATE NAMES:T4, Leu-3
ACCESSION NO.:P01730
GENE ID:920
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:CD4 is a 55 kDa type I transmembrane glycoprotein and a member of the Ig-SF of cell surface receptors. It is expressed predominantly on the “helper/inducer” subpopulation of mature T lymphocytes and on monocytes and macrophages. Domains 1 and 2 bind to MHC Class II antigens, while domains 3 and 4 may be involved in cis interactions with the CD3/TCR complex. CD4 functions as an accessory molecule in the recognition of foreign antigens in association with MHC class II antigens by T cells.

ANTIBODIES FOR RESEARCH USE ONLY.

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