CD3e Antibody [C363.29B] (Cy5) Cat. No.: 98-582

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psi-iconSpecifications
HOST SPECIES:Rat
SPECIES REACTIVITY: Mouse
IMMUNOGEN: IL-4 producing Th2 cell lines including D10
TESTED APPLICATIONS: ELISA, Flow
APPLICATIONS: CD3e Antibody [C363.29B] for use in flow cytometry and immunohistochemistry assays.
SPECIFICITY: CD3epsilon

psi-iconProperties
CLONALITY:Monoclonal
ISOTYPE:IgG2b
CONJUGATE:Cy5
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS/NaN3
CONCENTRATION:0.1 mg/mL
STORAGE CONDITIONS:Store vial at 2-8˚C

psi-iconAdditional Info
OFFICIAL SYMBOL:Cd3e
ALTERNATE NAMES:CD3 epsilon
ACCESSION NO.:P22646
GENE ID:12501
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25 kDa epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naïve T cell in vitro. Immobilized C363.2B9 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The monoclonal antibody is cytolytic, easily used for cell surface staining, and a good immunoprecipitating antibody.

ANTIBODIES FOR RESEARCH USE ONLY.

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