CD30 Antibody [mCD30.1] (FITC) Cat. No.: 98-728

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psi-iconSpecifications
HOST SPECIES:Hamster
SPECIES REACTIVITY: Mouse
IMMUNOGEN: Mouse CD30-mouse IgG1 fusion protein
TESTED APPLICATIONS: Drug Delivery, Flow, ICC
APPLICATIONS: CD30 Antibody [mCD30.1] for use in flow cytometry assays.
SPECIFICITY: CD30

psi-iconProperties
CLONALITY:Monoclonal
ISOTYPE:IgG
CONJUGATE:FITC
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS/NaN3
CONCENTRATION:0.5 mg/mL
STORAGE CONDITIONS:Store vial at 2-8˚C

psi-iconAdditional Info
OFFICIAL SYMBOL:Tnfrsf8
ALTERNATE NAMES:Ki-1, Ber-H2
ACCESSION NO.:Q60846
GENE ID:21941
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. Murine CD30 is expressed predominantly in the thymus and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. In anti-CD3epsilon-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN-gamma production. While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.

ANTIBODIES FOR RESEARCH USE ONLY.

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