CD3 delta / epsilon Heterodimer Recombinant Protein Cat. No.: 96-161

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psi-iconSpecifications
SPECIES:Cynomolgus monkey
SOURCE SPECIES:HEK293 cells
SEQUENCE:Glu 296 - Gly 580
FUSION TAG:His, DDDK Tag
TESTED APPLICATIONS:WB
APPLICATIONS:This recombinant protein can be used for WB. For research use only.
psi-iconProperties
PURITY:>92% as determined by SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:15.5 kDa (CD3E) and 14.5 kDa (CD3D)
PHYSICAL STATE:Lyophilized
BUFFER:PBS, pH7.4
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:CD3E & CD3D, CD3 delta & CD3 epsilon, CD3 delta / epsilon
ACCESSION NO.:Q95LI5 (CD3E) and Q95LI8 (CD3D)
OFFICIAL SYMBOL:CD3E; CD3D
GENE ID:102133065; 102133701
psi-iconBackground and References
BACKGROUND:T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
REFERENCES:1) Gold DP, et al., 1986, Nature 321 (6068): 431–4.
2) Clevers HC, et al., 1988, Proc. Natl. Acad. Sci. U.S.A. 85 (21): 8156–60.
3) Gil J, et al., 2011, J Clin Invest, 121(10):3872-6.
4) Lu X, et al.,2011, Hematology, 16(3):185-9.

FOR RESEARCH USE ONLY.

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