CD3 Antibody [UCHT1] (Cy5) Cat. No.: 99-419

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psi-iconSpecifications
HOST SPECIES:Mouse
SPECIES REACTIVITY: Human
IMMUNOGEN: Human peripheral blood lymphocytes from a patient with S├ęzary's syndrome and infant thymocytes
TESTED APPLICATIONS: Flow
APPLICATIONS: CD3 Antibody [UCHT1] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
SPECIFICITY: CD3

psi-iconProperties
CLONALITY:Monoclonal
ISOTYPE:IgG1
CONJUGATE:Cy5
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS/NaN3
CONCENTRATION:Lot specific
STORAGE CONDITIONS:Store vial at 2-8˚C

psi-iconAdditional Info
OFFICIAL SYMBOL:CD3E
ALTERNATE NAMES:CD3epsilon, T3E, TCRE, Leu-4, T3
ACCESSION NO.:P07766
GENE ID:916
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa epsilon chain of the CD3/TCR complex.

ANTIBODIES FOR RESEARCH USE ONLY.

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