CD160 Recombinant Protein Cat. No.: 96-842

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:HEK293 cells
SEQUENCE:Ile 27 - Ser 159
FUSION TAG:His Tag
TESTED APPLICATIONS:ELISA, WB
APPLICATIONS:This recombinant protein can be used for E, WB. For research use only.
BIOLOGICAL ACTIVITY: Measured by its binding ability in a functional ELISA. Immobilized Human HVEM, Strep Tag at 10 ug/mL (100 uL/well) can bind Human CD160, His Tag with a linear range of 0.2-1.3 ug/mL (QC tested).
psi-iconProperties
PURITY:>90% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
PREDICTED MOLECULAR WEIGHT:16.7 kDa
PHYSICAL STATE:Lyophilized
BUFFER:PBS, pH7.4
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:CD160,BY55,NK1,NK28
ACCESSION NO.:NP_008984.1
OFFICIAL SYMBOL:CD160
GENE ID:11126
psi-iconBackground and References
BACKGROUND:CD160 antigen is also known as natural killer cell receptor BY55, is a 27 kDa glycoprotein, contains 1 Ig-like V-type (immunoglobulin-like) domain. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. When expressed on vascular endothelial cells, CD160 propagates anti-angiogenic signals and promotes apoptosis.
REFERENCES:1) Anumanthan A., et al., 1998, J. Immunol. 161:2780-2790.
2) Agrawal S., et al., 1999, J. Immunol. 162:1223-1226.

FOR RESEARCH USE ONLY.

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