Specifications
| HOST SPECIES: | Mouse |
| SPECIES REACTIVITY: |
Baboon, Chimpanzee, Human, Porcine |
| IMMUNOGEN: |
Rheumatoid synovial cells and human monocytes |
| TESTED APPLICATIONS: |
Activity, Costimulation, Flow, IP |
| APPLICATIONS: |
CD11b Antibody [ICRF44] for use in flow cytometry, immunohistochemistry / immunocytochemistry and western blotting assays. |
| SPECIFICITY: |
CD11b |
Properties
| CLONALITY: | Monoclonal |
| ISOTYPE: | IgG1 |
| CONJUGATE: | FITC |
| PHYSICAL STATE: | Liquid |
| BUFFER: | Supplied in PBS/NaN3 |
| CONCENTRATION: | Lot specific |
| STORAGE CONDITIONS: | Store vial at 2-8˚C |
Additional Info
| OFFICIAL SYMBOL: | ITGAM |
| ALTERNATE NAMES: | Mac-1alpha, Mo-1, CR3, integrin alphaM, C3biR, ITGAM, CR3A, p170 |
| ACCESSION NO.: | P11215 |
| GENE ID: | 3684 |
| USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
Background and References
| BACKGROUND: | CD11b is the 165 kDa alphaM chain which combines with the CD18 beta2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2). |
ANTIBODIES FOR RESEARCH USE ONLY.
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