Specifications
HOST SPECIES: | Mouse |
SPECIES REACTIVITY: |
Baboon, Chimpanzee, Human, Porcine |
IMMUNOGEN: |
Rheumatoid synovial cells and human monocytes |
TESTED APPLICATIONS: |
Activity, Costimulation, Flow, IP |
APPLICATIONS: |
CD11b Antibody [ICRF44] for use in flow cytometry, immunohistochemistry / immunocytochemistry and western blotting assays. |
SPECIFICITY: |
CD11b |
Properties
CLONALITY: | Monoclonal |
ISOTYPE: | IgG1 |
CONJUGATE: | FITC |
PHYSICAL STATE: | Liquid |
BUFFER: | Supplied in PBS/NaN3 |
CONCENTRATION: | Lot specific |
STORAGE CONDITIONS: | Store vial at 2-8˚C |
Additional Info
OFFICIAL SYMBOL: | ITGAM |
ALTERNATE NAMES: | Mac-1alpha, Mo-1, CR3, integrin alphaM, C3biR, ITGAM, CR3A, p170 |
ACCESSION NO.: | P11215 |
GENE ID: | 3684 |
USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
Background and References
BACKGROUND: | CD11b is the 165 kDa alphaM chain which combines with the CD18 beta2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2). |
ANTIBODIES FOR RESEARCH USE ONLY.
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