CD11b Antibody [ICRF44] (FITC) Cat. No.: 99-462

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psi-iconSpecifications
HOST SPECIES:Mouse
SPECIES REACTIVITY: Baboon, Chimpanzee, Human, Porcine
IMMUNOGEN: Rheumatoid synovial cells and human monocytes
TESTED APPLICATIONS: Activity, Costimulation, Flow, IP
APPLICATIONS: CD11b Antibody [ICRF44] for use in flow cytometry, immunohistochemistry / immunocytochemistry and western blotting assays.
SPECIFICITY: CD11b

psi-iconProperties
CLONALITY:Monoclonal
ISOTYPE:IgG1
CONJUGATE:FITC
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS/NaN3
CONCENTRATION:Lot specific
STORAGE CONDITIONS:Store vial at 2-8˚C

psi-iconAdditional Info
OFFICIAL SYMBOL:ITGAM
ALTERNATE NAMES:Mac-1alpha, Mo-1, CR3, integrin alphaM, C3biR, ITGAM, CR3A, p170
ACCESSION NO.:P11215
GENE ID:3684
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:CD11b is the 165 kDa alphaM chain which combines with the CD18 beta2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).

ANTIBODIES FOR RESEARCH USE ONLY.

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