CD11b Antibody [3A33] (Cy5) Cat. No.: 98-639

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psi-iconSpecifications
HOST SPECIES:Rat
SPECIES REACTIVITY: Mouse
IMMUNOGEN: Peritoneal macrophages from B6D2 hybrid mice
TESTED APPLICATIONS: ELISA, Flow, IP, Multiplex
APPLICATIONS: CD11b Antibody [3A33] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
SPECIFICITY: CD11b

psi-iconProperties
CLONALITY:Monoclonal
ISOTYPE:IgG2a
CONJUGATE:Cy5
PHYSICAL STATE:Liquid
BUFFER:Supplied in PBS/NaN3
CONCENTRATION:0.1 mg/mL
STORAGE CONDITIONS:Store vial at 2-8˚C

psi-iconAdditional Info
OFFICIAL SYMBOL:Itgam
ALTERNATE NAMES:Integrin alphaM, Mac-1alpha, Mac-1, Mo1, CR3, C3biR
ACCESSION NO.:P05555
GENE ID:16409
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:CD11b (integrin alphaM subunit) combines with CD18 (integrin beta2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.

ANTIBODIES FOR RESEARCH USE ONLY.

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