CCL4 Antibody Cat. No.: XW-7720

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psi-iconSpecifications
HOST SPECIES:Chicken
SPECIES REACTIVITY: Human
IMMUNOGEN: 27-92
TESTED APPLICATIONS: ELISA, WB
APPLICATIONS: Small inducible cytokine A4 antibody can be used for the detection of Small inducible cytokine A4 by ELISA and Western Blot, may also work for ICC and IHC.
PREDICTED MOLECULAR WEIGHT: 10.2 kDa (calculated)

psi-iconProperties
PURIFICATION:Immunoaffinity Purified
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Phosphate-Buffered Saline. No preservatives added.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:CCL4 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:CCL4
ALTERNATE NAMES:LAG1, MIP1B, SCYA4, C-C motif chemokine 4, G-26 T-lymphocyte-secreted protein, LAG-1, ACT2, G-26, HC21, LAG1, SCYA2, MIP1B1, AT744.1, MIP-1-beta, Small inducible cytokine A4, CCL4, Macrophage inflammatory protein 1-beta, MIP-1-beta(1-69), T-cell activation protein 2, ACT-2, PAT 744, H400, SIS-gamma, Lymphocyte activation gene 1 protein, G-26 T lymphocyte-secreted protein
ACCESSION NO.:NP_002975.1
PROTEIN GI NO.:4506845
GENE ID:6351
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:FUNCTION: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T cells. Recombinant MIP-1-β induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-β(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T cells. MIP-1-β(3-69) is also a ligand for CCR1 and CCR2 isoform B.

ANTIBODIES FOR RESEARCH USE ONLY.

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