CCL24 Recombinant Protein Cat. No.: 90-389

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:CHO cells
SEQUENCE:The extracellular domain of human CCL24 (aa 27-119) is fused to the N-terminus of the Fc region of human IgG1.
FUSION TAG:Fc Tag
TESTED APPLICATIONS:
APPLICATIONS:This recombinant proteins is for research use only.
BIOLOGICAL ACTIVITY: N/A
psi-iconProperties
PURITY:>98% (SDS-PAGE).

Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
PHYSICAL STATE:Lyophilized
BUFFER:Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 μl sterile water. Add 1X PBS to the desired protein concentration.
STORAGE CONDITIONS:Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
psi-iconAdditional Info
ALTERNATE NAMES:Eotaxin-2, C-C Motif Chemokine 24, Eosinophil Chemotactic Protein 2, Myeloid Progenitor Inhibitory Factor 2, MPIF-2, Small-inducible Cytokine A24, CKbeta6
ACCESSION NO.:AAH69391
PROTEIN GI NO.:47479827
OFFICIAL SYMBOL:CCL24
GENE ID:6369
psi-iconBackground and References
BACKGROUND:CCL24 (eotaxin-2) has been shown to induce chemotaxis of eosinophils, basophils and resting T lymphocytes but not monocytes and activated T lymphocytes. CCL24 is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated levels of CCL24 has been seen in patients with aspirin-exacerbated respiratory disease (AERD), such as asthma.

FOR RESEARCH USE ONLY.

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